HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: S10A3 (P33764)
Protein S100-A3 (Protein S-100E) (S100 calcium-binding protein A3)
Gene: S100A3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31837246
Identification Methods	fluorescence polarization spectroscopy
Interaction Type	physical association

Property	Details
Interacting Pfam domains	S_100~TAD2
Common GO terms	GO:0005829 - cytosol
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 101
+	Hs
		413199 P53_HUMAN (1-393): 0: 619: 100.00		S10A1_HUMAN (1-90): 1.78e-38: 125: 42.22
+	Hs
		413232 P53_HUMAN (1-393): 0: 619: 100.00		S10A4_HUMAN (1-98): 1.54e-38: 125: 45.92
+	Hs
		413280 P53_HUMAN (1-393): 0: 619: 100.00		S10AB_HUMAN (2-99): 2.87e-37: 122: 29.29
+	Hs
		413250 P53_HUMAN (1-393): 0: 619: 100.00		S10A2_HUMAN (1-97): 1.12e-36: 121: 43.30
+	Hs
		414148 P53_HUMAN (1-393): 0: 619: 100.00		HORN_HUMAN (1-88): 2.01e-32: 120: 28.41
+	Hs
		413227 P53_HUMAN (1-393): 0: 619: 100.00		S100P_HUMAN (3-91): 5.35e-36: 119: 33.71
+	Hs
		413509 P53_HUMAN (1-393): 0: 619: 100.00		S10AA_HUMAN (1-90): 4.74e-34: 114: 27.78
+	Hs
		407558 P53_HUMAN (1-393): 0: 619: 100.00		S100B_HUMAN (3-91): 1.64e-32: 110: 38.20
+	Hs
		413967 P53_HUMAN (1-393): 0: 619: 100.00		FILA2_HUMAN (3-101): 3.28e-28: 108: 25.25
+	Hs
		413609 P53_HUMAN (1-393): 0: 619: 100.00		S10AC_HUMAN (3-91): 2.16e-31: 107: 31.46
+	Hs
		413018 P53_HUMAN (1-393): 0: 619: 100.00		S10A6_HUMAN (1-92): 2.03e-30: 104: 44.57
+	Hs
		413004 P53_HUMAN (1-393): 0: 619: 100.00		S10A8_HUMAN (1-97): 1.23e-29: 103: 20.62
+	Hs
		413286 P53_HUMAN (1-393): 0: 619: 100.00		S10A5_HUMAN (1-90): 4.01e-27: 96.9: 42.22
+	Hs
		414480 P53_HUMAN (1-393): 0: 619: 100.00		S10AD_HUMAN (3-84): 2.04e-25: 92.6: 30.49
+	Hs
		414397 P53_HUMAN (1-393): 0: 619: 100.00		S10AG_HUMAN (3-96): 3.79e-25: 92.3: 24.21