Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: FAK1 (Q05397)
Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion kinase-related nonkinase) (FRNK) (Protein phosphatase 1 regulatory subunit 71) (PPP1R71) (Protein-tyrosine kinase 2) (p125FAK) (pp125FAK)
Gene: PTK2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.82 0.60 0.705

The method score is based on:

Property Details
Experiments 27736841, 15855171, 18206965, 19857493
Identification Methods affinity chromatography technology, pull down, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005813 - centrosome
GO:0005829 - cytosol
GO:0007179 - transforming growth factor beta receptor signaling pathway
GO:0043066 - negative regulation of apoptotic process
and 1 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 393
Hs

1 1052
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
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+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025