HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: MAML1 (Q92585)
Mastermind-like protein 1 (Mam-1)
Gene: MAML1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	17317671, 38580884
Identification Methods	pull down, affinity chromatography technology, proximity labelling technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 1016
+	Hs
		413134 P53_HUMAN (1-393): 0: 619: 100.00		MUC1_HUMAN (56-1005): 2.25e-51: 199: 10.19
+	Hs
		414448 P53_HUMAN (1-393): 0: 619: 100.00		CIC_HUMAN (187-926): 1.94e-16: 87.3: 8.51
+	Mm
		382502 P53_MOUSE (1-393): 0: 589: 77.35		EP400_MOUSE (366-990): 3.94e-24: 112: 12.77
+	Hs
		414246 P53_HUMAN (1-393): 0: 619: 100.00		KMT2C_HUMAN (39-734): 3.4e-12: 73.4: 10.78
+	Hs
		413723 P53_HUMAN (1-393): 0: 619: 100.00		BPTF_HUMAN (342-959): 6.78e-12: 72.5: 14.33
+	Hs
		414071 P53_HUMAN (1-393): 0: 619: 100.00		SRCAP_HUMAN (279-761): 3.17e-11: 70.1: 13.29
+	Hs
		414185 P53_HUMAN (1-393): 0: 619: 100.00		KMT2E_HUMAN (318-985): 1.34e-10: 67.8: 15.84
+	Hs
		414757 P53_HUMAN (1-393): 0: 619: 100.00		CHD7_HUMAN (291-953): 5.1e-09: 63: 8.90
+	Hs
		186793 P73_HUMAN (13-362): 2.36e-166: 481: 39.74		CIC_HUMAN (187-926): 1.94e-16: 87.3: 8.51