HitPredict

Interactor 1: NPM (P06748)
Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Nucleolar protein NO38) (Numatrin)
Gene: NPM1

Interactor 2: RPP25 (Q9BUL9)
Ribonuclease P protein subunit p25 (RNase P protein subunit p25)
Gene: RPP25

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0005730 - nucleolus
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 294 Hs			1 199
+	Hs
		418457 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		RP25L_HUMAN (1-167): 4.16e-60: 187: 40.72
+	Hs
		271399 NPM3_HUMAN (10-119): 6.13e-58: 185: 43.75		RPP25_HUMAN (1-199): 9.04e-78: 232: 100.00
+	Hs
		271362 NPM3_HUMAN (10-119): 6.13e-58: 185: 43.75		RP25L_HUMAN (1-167): 4.16e-60: 187: 40.72