Protein: PTH1R
Parathyroid hormone/parathyroid hormone-related peptide receptor (PTH/PTHrP type I receptor) (PTH/PTHr receptor) (Parathyroid hormone 1 receptor) (PTH1 receptor)

Gene: PTH1R
Organism: Homo sapiens
Interactions: 88
UniProt ID: Q03431

Gene Ontology (top 5):
GO:0001501 - skeletal system development
GO:0001701 - in utero embryonic development
GO:0002062 - chondrocyte differentiation
GO:0002076 - osteoblast development
GO:0004991 - parathyroid hormone receptor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

377267

PTHY
Parathyroid hormone

2

1

Small-scale

0.828

High

552904

PTHR
Parathyroid hormone-related protein

2

0

Small-scale

0.777

High

1042734

PTH1R
Parathyroid hormone/parathyroid hormone-related peptide receptor

1

5

Small-scale

0.710

High

989833

GNAI1
Guanine nucleotide-binding protein G(i) subunit alpha-1

1

9

Small-scale

0.618

High

178625

DEGS1
Sphingolipid delta(4)-desaturase DES1

2

1

High-throughput

0.611

High

419989

B3A2
Anion exchange protein 2

2

4

High-throughput

0.611

High

931226

AT12A
Potassium-transporting ATPase alpha chain 2

2

6

High-throughput

0.611

High

1042751

ACD10
Acyl-CoA dehydrogenase family member 10

2

3

High-throughput

0.611

High

1042760

AT11C
Phospholipid-transporting ATPase IG

2

3

High-throughput

0.611

High

1042764

SPP2B
Signal peptide peptidase-like 2B

2

1

High-throughput

0.611

High

1042774

S47A1
Multidrug and toxin extrusion protein 1

2

1

High-throughput

0.611

High

1042780

SGPP1
Sphingosine-1-phosphate phosphatase 1

2

2

High-throughput

0.611

High

1042781

S12A9
Solute carrier family 12 member 9

2

13

High-throughput

0.611

High

1042785

AT132
Polyamine-transporting ATPase 13A2

2

13

High-throughput

0.611

High

1042787

FIRRM
FIGNL1-interacting regulator of recombination and mitosis

2

2

High-throughput

0.611

High

1042788

DJC17
DnaJ homolog subfamily C member 17

2

2

High-throughput

0.611

High

1042792

S12A4
Solute carrier family 12 member 4

2

13

High-throughput

0.611

High

1042797

ZNT1
Proton-coupled zinc antiporter SLC30A1

2

8

High-throughput

0.611

High

291776

STK16
Serine/threonine-protein kinase 16

2

3

High-throughput

0.606

High

1042770

SMRC1
SWI/SNF complex subunit SMARCC1

2

1

High-throughput

0.606

High

1042761

SIDT2
SID1 transmembrane family member 2

2

0

High-throughput

0.585

High

1042767

CTL1
Choline transporter-like protein 1

2

0

High-throughput

0.585

High

1042791

CCPG1
Cell cycle progression protein 1

2

0

High-throughput

0.585

High

885221

HXA1
Homeobox protein Hox-A1

2

0

High-throughput

0.580

High

1042738

MKRN3
E3 ubiquitin-protein ligase makorin-3

2

0

High-throughput

0.580

High

1042766

TEKT4
Tektin-4

2

0

High-throughput

0.580

High

162822

NHRF1
Na(+)/H(+) exchange regulatory cofactor NHE-RF1

1

20

Small-scale

0.561

High

1042744

NHRF2
Na(+)/H(+) exchange regulatory cofactor NHE-RF2

1

20

Small-scale

0.561

High

248583

FADS1
Acyl-CoA

2

2

High-throughput

0.558

High

773865

SOAT1
Sterol O-acyltransferase 1

2

2

High-throughput

0.558

High

1042748

AG10A
Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase

2

3

High-throughput

0.558

High

1042765

PIGO
GPI ethanolamine phosphate transferase 3, catalytic subunit

2

9

High-throughput

0.558

High

1042772

EVI5L
EVI5-like protein

2

4

High-throughput

0.558

High

1042775

MBOA7
Membrane-bound acylglycerophosphatidylinositol O-acyltransferase MBOAT7

2

3

High-throughput

0.558

High

1042784

PCX3
Pecanex-like protein 3

2

2

High-throughput

0.558

High

1042794

TMX2
Thioredoxin-related transmembrane protein 2

2

2

High-throughput

0.558

High

245458

OPA1
Dynamin-like GTPase OPA1, mitochondrial

1

1

High-throughput

0.536

High

1042740

ATM
Serine-protein kinase ATM

1

6

High-throughput

0.536

High

1042741

MTX1
Metaxin-1

1

4

High-throughput

0.536

High

1042742

MTR1L
Melatonin-related receptor

1

6

High-throughput

0.536

High

1042743

KCC1A
Calcium/calmodulin-dependent protein kinase type 1

1

1

High-throughput

0.536

High

1042753

RINT1
RAD50-interacting protein 1

1

1

High-throughput

0.536

High

1042754

MZT2B
Mitotic-spindle organizing protein 2B

1

3

High-throughput

0.536

High

1042758

DYM
Dymeclin

1

3

High-throughput

0.536

High

1042759

INT1
Integrator complex subunit 1

1

4

High-throughput

0.536

High

1042762

EXOC6
Exocyst complex component 6

1

1

High-throughput

0.536

High

1042763

GOGA5
Golgin subfamily A member 5

1

3

High-throughput

0.536

High

1042773

COQ8B
Atypical kinase COQ8B, mitochondrial

1

5

High-throughput

0.536

High

1042777

CP2S1
Cytochrome P450 2S1

1

4

High-throughput

0.536

High

1042790

VATH
V-type proton ATPase subunit H

1

2

High-throughput

0.536

High

1042793

S22AE
Solute carrier family 22 member 14

1

6

High-throughput

0.515

High

319692

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.513

High

1042768

ATRIP
ATR-interacting protein

1

0

High-throughput

0.513

High

1042771

INT12
Integrator complex subunit 12

1

0

High-throughput

0.513

High

507858

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

2

High-throughput

0.501

High

173694

BTAF1
TATA-binding protein-associated factor 172

1

4

High-throughput

0.489

High

397599

NU1M
NADH-ubiquinone oxidoreductase chain 1

1

1

High-throughput

0.489

High

1042747

FAKD1
FAST kinase domain-containing protein 1, mitochondrial

1

6

High-throughput

0.489

High

1042750

ATD3C
ATPase family AAA domain-containing protein 3C

1

1

High-throughput

0.489

High

1042755

MBOA5
Lysophospholipid acyltransferase 5

1

3

High-throughput

0.489

High

1042756

PDXD1
Pyridoxal-dependent decarboxylase domain-containing protein 1

1

2

High-throughput

0.489

High

1042783

TFB2M
Dimethyladenosine transferase 2, mitochondrial

1

2

High-throughput

0.489

High

1042789

ORML1
ORM1-like protein 1

1

1

High-throughput

0.489

High

1042735

1433F
14-3-3 protein eta

1

0

Small-scale

0.480

High

228076

PM34
Peroxisomal membrane protein PMP34

1

5

High-throughput

0.479

High

467465

4F2
Amino acid transporter heavy chain SLC3A2

1

1

High-throughput

0.479

High

779703

MOT8
Monocarboxylate transporter 8

1

4

High-throughput

0.479

High

814789

CUX1
Homeobox protein cut-like 1

1

1

High-throughput

0.479

High

996112

EF1A1
Elongation factor 1-alpha 1

1

2

High-throughput

0.479

High

1042736

EF1A2
Elongation factor 1-alpha 2

1

2

High-throughput

0.479

High

1042739

CLN3
Battenin

1

3

High-throughput

0.479

High

1042749

S27A3
Long-chain fatty acid transport protein 3

1

4

High-throughput

0.479

High

1042778

ABCA3
Phospholipid-transporting ATPase ABCA3

1

2

High-throughput

0.479

High

1042786

PLCC
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma

1

7

High-throughput

0.479

High

1042795

S12A7
Solute carrier family 12 member 7

1

11

High-throughput

0.479

High

1042737

SRBP2
Sterol regulatory element-binding protein 2

1

0

High-throughput

0.458

High

1042745

KCNJ8
ATP-sensitive inward rectifier potassium channel 8

1

0

High-throughput

0.458

High

764682

CTNB1
Catenin beta-1

1

0

Small-scale

0.438

High

1042752

RETST
All-trans-retinol 13,14-reductase

1

1

High-throughput

0.437

High

1042757

CERS6
Ceramide synthase 6

1

8

High-throughput

0.437

High

1042769

BRI3B
BRI3-binding protein

1

2

High-throughput

0.437

High

1042796

ALG6
Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase

1

2

High-throughput

0.437

High

1042779

F118B
Protein FAM118B

2

0

High-throughput

0.318

High

350447

GPAN1
G patch domain and ankyrin repeat-containing protein 1

2

0

High-throughput

0.316

High

1042776

GUCD1
Protein GUCD1

2

0

High-throughput

0.316

High

1042746

MGT5B
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B

1

0

High-throughput

0.251

Low

1042782

PIGM
GPI alpha-1,4-mannosyltransferase I, catalytic subunit

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025