Interactor 1: GNAI1 (P63096)
Guanine nucleotide-binding protein G(i) subunit alpha-1 (EC 3.6.5.-) (Adenylate cyclase-inhibiting G alpha protein)
Gene: GNAI1
Interactor 2: PTH1R (Q03431)
Parathyroid hormone/parathyroid hormone-related peptide receptor (PTH/PTHrP type I receptor) (PTH/PTHr receptor) (Parathyroid hormone 1 receptor) (PTH1 receptor)
Gene: PTH1R
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 16099817 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | 7tm_2~G-alpha |
| Common GO terms | GO:0005730 - nucleolus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0007186 - G protein-coupled receptor signaling pathway and 1 others more... |
| Homologous interactions | 9 |
Homologous interactions
Color coding for hit scores 
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Last updated: 11Aug2025