Protein: CRFR1
Corticotropin-releasing factor receptor 1 (CRF-R-1) (CRF-R1) (CRFR-1) (Corticotropin-releasing hormone receptor 1) (CRH-R-1) (CRH-R1)

Gene: CRFR1, CRHR1
Organism: Homo sapiens
Interactions: 20
UniProt ID: P34998

Gene Ontology (top 5):
GO:0004930 - G protein-coupled receptor activity
GO:0005768 - endosome
GO:0005886 - plasma membrane
GO:0006955 - immune response
GO:0007166 - cell surface receptor signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

449485

CRF
Corticoliberin

5

1

Small-scale

0.926

High

762196

UCN1
Urocortin

2

3

Small-scale

0.778

High

762201

DLG1
Disks large homolog 1

2

9

Small-scale

0.629

High

418605

GNAI2
Guanine nucleotide-binding protein G(i) subunit alpha-2

1

9

Small-scale

0.618

High

482578

GNAO
Guanine nucleotide-binding protein G(o) subunit alpha

1

5

Small-scale

0.618

High

762195

GNAQ
Guanine nucleotide-binding protein G(q) subunit alpha

1

9

Small-scale

0.618

High

762197

GNAS2
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short

1

9

Small-scale

0.618

High

762198

GNAI1
Guanine nucleotide-binding protein G(i) subunit alpha-1

1

9

Small-scale

0.618

High

762199

DLG4
Disks large homolog 4

2

10

Small-scale

0.595

High

762207

SRPK1
SRSF protein kinase 1

1

1

High-throughput

0.550

High

299743

MPDZ
Multiple PDZ domain protein

1

20

Small-scale

0.501

High

732444

ARRB2
Beta-arrestin-2

1

3

Small-scale

0.501

High

762194

ARRB1
Beta-arrestin-1

1

3

Small-scale

0.501

High

762200

PTN13
Tyrosine-protein phosphatase non-receptor type 13

1

3

Small-scale

0.501

High

762202

SCRIB
Protein scribble homolog

1

13

High-throughput

0.501

High

762203

NHRF3
Na(+)/H(+) exchange regulatory cofactor NHE-RF3

1

20

Small-scale

0.501

High

762204

MAGI3
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3

1

20

Small-scale

0.501

High

762205

MAGI2
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2

1

20

Small-scale

0.501

High

762206

MAGI1
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1

1

20

Small-scale

0.501

High

762208

GOPC
Golgi-associated PDZ and coiled-coil motif-containing protein

1

20

Small-scale

0.501

High


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Last updated: 11Aug2025