Protein: RFC1
Replication factor C subunit 1 (Replication factor C1) (Activator 1 95 kDa subunit) (Cell division control protein 44)

Gene: RFC1
Organism: Saccharomyces cerevisiae S288C
Interactions: 107
UniProt ID: P38630

Gene Ontology (top 5):
GO:0000278 - mitotic cell cycle
GO:0003677 - DNA binding
GO:0003689 - DNA clamp loader activity
GO:0005524 - ATP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

800996

RFC2
Replication factor C subunit 2

7

20

Small-scale

0.949

High

586454

PCNA
Proliferating cell nuclear antigen

5

17

Small-scale

0.921

High

796694

RFC5
Replication factor C subunit 5

4

20

High-throughput

0.896

High

800943

RFC3
Replication factor C subunit 3

3

18

High-throughput

0.855

High

800994

RFC4
Replication factor C subunit 4

3

20

High-throughput

0.855

High

800995

ATAD2
ATPase histone chaperone YTA7

2

8

High-throughput

0.754

High

419719

H2A2
Histone H2A.2

4

9

High-throughput

0.691

High

382074

H4
Histone H4

3

9

High-throughput

0.650

High

793820

DPOA2
DNA polymerase alpha subunit B

2

2

High-throughput

0.621

High

744194

RAD24
Checkpoint protein RAD24

1

18

Small-scale

0.618

High

801024

PDP3
NuA3 HAT complex component PDP3

2

2

Small-scale

0.611

High

739619

SPT16
FACT complex subunit SPT16

2

1

High-throughput

0.584

High

801002

DSN1
Kinetochore-associated protein DSN1

2

4

High-throughput

0.584

High

801033

SMT3
Ubiquitin-like protein SMT3

2

4

Small-scale

0.584

High

509526

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

7

High-throughput

0.575

High

752206

HSP78
Heat shock protein 78, mitochondrial

1

7

High-throughput

0.575

High

544716

SSB1
Ribosome-associated molecular chaperone SSB1

1

14

High-throughput

0.536

High

721901

XPO1
Exportin-1

1

6

High-throughput

0.536

High

801004

ECO1
N-acetyltransferase ECO1

1

4

Small-scale

0.515

High

801018

HMO1
High mobility group protein 1

1

10

High-throughput

0.515

High

677923

YCQ6
Uncharacterized protein YCR016W

1

0

High-throughput

0.493

High

801006

RSSA2
Small ribosomal subunit protein uS2B

1

6

High-throughput

0.489

High

801008

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

2

High-throughput

0.489

High

800990

LIN1
Protein LIN1

1

0

Small-scale

0.486

High

381090

H2B1
Histone H2B.1

1

20

High-throughput

0.479

High

381506

H2B2
Histone H2B.2

1

20

High-throughput

0.479

High

416813

DNLI1
DNA ligase 1

1

3

Small-scale

0.479

High

435059

RS3
Small ribosomal subunit protein uS3

1

3

High-throughput

0.479

High

441118

KAPA
cAMP-dependent protein kinase type 1

1

4

Small-scale

0.479

High

448961

TOP2
DNA topoisomerase 2

1

1

High-throughput

0.479

High

579319

HSC82
ATP-dependent molecular chaperone HSC82

1

14

High-throughput

0.479

High

594350

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

3

High-throughput

0.479

High

670653

SIS1
Protein SIS1

1

6

High-throughput

0.479

High

706981

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.479

High

734956

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

3

High-throughput

0.479

High

736642

ASF1
Histone chaperone ASF1

1

4

Small-scale

0.479

High

744294

CHD1
Chromo domain-containing protein 1

1

6

High-throughput

0.479

High

745721

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

5

High-throughput

0.479

High

792016

GBLP
Small ribosomal subunit protein RACK1

1

13

High-throughput

0.479

High

794171

ISW1
ISWI chromatin-remodeling complex ATPase ISW1

1

8

High-throughput

0.479

High

800991

MLH1
DNA mismatch repair protein MLH1

1

6

Small-scale

0.479

High

800999

ULP2
Ubiquitin-like-specific protease 2

1

4

High-throughput

0.479

High

801000

MPH1
ATP-dependent DNA helicase MPH1

1

1

High-throughput

0.479

High

801005

RSC8
Chromatin structure-remodeling complex protein RSC8

1

2

High-throughput

0.479

High

801009

HFM1
ATP-dependent DNA helicase MER3

1

7

Small-scale

0.479

High

801011

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

11

Small-scale

0.479

High

801012

APJ1
J domain-containing protein APJ1

1

6

High-throughput

0.479

High

801013

H3
Histone H3

1

20

High-throughput

0.479

High

801016

HOS3
Histone deacetylase HOS3

1

2

High-throughput

0.479

High

801019

SIZ1
E3 SUMO-protein ligase SIZ1

1

4

High-throughput

0.479

High

801021

DPB4
DNA polymerase epsilon subunit D

1

1

Small-scale

0.479

High

801022

ARP9
Actin-like protein ARP9

1

2

High-throughput

0.479

High

801026

SGO1
Shugoshin

1

3

High-throughput

0.479

High

801028

ELG1
Telomere length regulation protein ELG1

1

18

High-throughput

0.479

High

801030

MLH3
DNA mismatch repair protein MLH3

1

6

Small-scale

0.479

High

801032

SIZ2
E3 SUMO-protein ligase SIZ2

1

4

High-throughput

0.479

High

801036

ARP7
Actin-related protein 7

1

2

High-throughput

0.479

High

801038

CMR1
DNA damage-binding protein CMR1

1

7

High-throughput

0.479

High

557701

SRS2
ATP-dependent DNA helicase SRS2

1

0

High-throughput

0.458

High

646388

RAD53
Serine/threonine-protein kinase RAD53

1

0

High-throughput

0.458

High

694539

SPT5
Transcription elongation factor SPT5

1

0

High-throughput

0.458

High

801017

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

0

High-throughput

0.458

High

801023

NHEJ1
Non-homologous end-joining protein 1

1

0

Small-scale

0.458

High

801031

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

801035

HAT1
Histone acetyltransferase type B catalytic subunit

1

0

High-throughput

0.458

High

801037

EAF3
Chromatin modification-related protein EAF3

1

0

High-throughput

0.458

High

523808

HSP71
Heat shock protein SSA1

1

11

High-throughput

0.445

High

526579

HSP72
Heat shock protein SSA2

1

11

High-throughput

0.445

High

741489

HSP7F
Heat shock protein homolog SSE1

1

14

High-throughput

0.445

High

800993

SSB2
Ribosome-associated molecular chaperone SSB2

1

14

High-throughput

0.445

High

149731

RS9A
Small ribosomal subunit protein uS4A

1

3

High-throughput

0.437

High

383674

RS17A
Small ribosomal subunit protein eS17A

1

3

High-throughput

0.437

High

410100

RL25
Large ribosomal subunit protein uL23

1

3

High-throughput

0.437

High

433612

RL26A
Large ribosomal subunit protein uL24A

1

7

High-throughput

0.437

High

435933

RS13
Small ribosomal subunit protein uS15

1

3

High-throughput

0.437

High

441882

RS14A
Small ribosomal subunit protein uS11A

1

3

High-throughput

0.437

High

455034

RS19A
Small ribosomal subunit protein eS19A

1

4

High-throughput

0.437

High

503014

RS22A
Small ribosomal subunit protein uS8A

1

3

High-throughput

0.437

High

504184

RL31A
Large ribosomal subunit protein eL31A

1

5

High-throughput

0.437

High

512411

RS6A
Small ribosomal subunit protein eS6A

1

5

High-throughput

0.437

High

512980

RS8A
Small ribosomal subunit protein eS8A

1

5

High-throughput

0.437

High

514612

RS18A
Small ribosomal subunit protein uS13A

1

2

High-throughput

0.437

High

674593

RS2
Small ribosomal subunit protein uS5

1

4

High-throughput

0.437

High

676833

DCC1
Sister chromatid cohesion protein DCC1

1

8

High-throughput

0.437

High

689424

RS7A
Small ribosomal subunit protein eS7A

1

4

High-throughput

0.437

High

747332

RSSA1
Small ribosomal subunit protein uS2A

1

6

High-throughput

0.437

High

753342

RS3A1
Small ribosomal subunit protein eS1A

1

4

High-throughput

0.437

High

778297

RS27A
Small ribosomal subunit protein eS27A

1

2

High-throughput

0.437

High

794965

NU170
Nucleoporin NUP170

1

6

High-throughput

0.437

High

795319

ATG8
Autophagy-related protein 8

1

4

High-throughput

0.437

High

800989

RS20
Small ribosomal subunit protein uS10

1

3

High-throughput

0.437

High

800992

LAA1
AP-1 accessory protein LAA1

1

3

High-throughput

0.437

High

800997

MAM33
Mitochondrial acidic protein MAM33

1

1

High-throughput

0.437

High

801003

RL10
Large ribosomal subunit protein uL16

1

3

High-throughput

0.437

High

801007

RS12
Small ribosomal subunit protein eS12

1

3

High-throughput

0.437

High

801010

RL26B
Large ribosomal subunit protein uL24B

1

7

High-throughput

0.437

High

801014

NUM1
Nuclear migration protein NUM1

1

2

High-throughput

0.437

High

801015

RS15
Small ribosomal subunit protein uS19

1

3

High-throughput

0.437

High

801025

VAM6
Vacuolar morphogenesis protein 6

1

3

High-throughput

0.437

High

801027

RS10A
Small ribosomal subunit protein eS10A

1

3

High-throughput

0.437

High

394510

EF1A
Elongation factor 1-alpha

1

3

High-throughput

0.407

High

801001

DJP1
DnaJ-like protein 1

1

5

High-throughput

0.407

High

801034

HSP42
Heat shock protein 42

1

2

High-throughput

0.407

High

434556

RL22A
Large ribosomal subunit protein eL22A

1

0

High-throughput

0.249

Low

800998

RL34B
Large ribosomal subunit protein eL34B

1

0

High-throughput

0.249

Low

801020

IOC4
ISWI one complex protein 4

1

0

High-throughput

0.249

Low

801029

IOC2
ISWI one complex protein 2

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025