HitPredict

Interactor 1: TPM3 (P06753)
Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3) (Tropomyosin-5) (hTM5)
Gene: TPM3

Interactor 2: RHOV (Q96L33)
Rho-related GTP-binding protein RhoV (CDC42-like GTPase 2) (GTP-binding protein-like 2) (Rho GTPase-like protein ARHV) (Wnt-1 responsive Cdc42 homolog 2) (WRCH-2)
Gene: RHOV

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007015 - actin filament organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 285 Hs			1 236
+	Hs
		418991 TPM3_HUMAN (1-285): 3.63e-44: 153: 100.00		RHOU_HUMAN (32-236): 2.81e-89: 265: 60.48
+	Hs
		418937 TPM3_HUMAN (1-285): 3.63e-44: 153: 100.00		RHOG_HUMAN (31-210): 1.12e-78: 236: 49.44
+	Hs
		932019 TPM4_HUMAN (43-285): 1.76e-33: 124: 69.96		RHOU_HUMAN (32-236): 2.81e-89: 265: 60.48
+	Hs
		451303 TPM1_HUMAN (2-285): 2.54e-44: 153: 91.20		RHOV_HUMAN (1-236): 3.37e-76: 231: 100.00
+	Hs
		1132655 FKB15_HUMAN (1-284): 5.16e-27: 112: 13.40		RHOU_HUMAN (32-236): 2.81e-89: 265: 60.48
+	Hs
		931991 TPM4_HUMAN (43-285): 1.76e-33: 124: 69.96		RHOG_HUMAN (31-210): 1.12e-78: 236: 49.44
+	Hs
		451225 TPM1_HUMAN (2-285): 2.54e-44: 153: 91.20		CDC42_HUMAN (32-207): 2.12e-66: 205: 57.39
+	Hs
		932039 TPM4_HUMAN (43-285): 1.76e-33: 124: 69.96		RHOV_HUMAN (1-236): 3.37e-76: 231: 100.00
+	Hs
		925177 TPM4_HUMAN (43-285): 1.76e-33: 124: 69.96		RAC1_HUMAN (32-217): 3.34e-76: 230: 53.23
+	Hs
		1150629 MRCKG_HUMAN (3-285): 1.48e-14: 75.7: 10.65		RHOV_HUMAN (1-236): 3.37e-76: 231: 100.00
+	Hs
		925356 MRCKG_HUMAN (3-285): 1.48e-14: 75.7: 10.65		RAC1_HUMAN (32-217): 3.34e-76: 230: 53.23
+	Hs
		951494 MRCKB_HUMAN (12-285): 1.02e-11: 67.2: 14.92		RHOG_HUMAN (31-210): 1.12e-78: 236: 49.44
+	Hs
		564571 MRCKG_HUMAN (3-285): 1.48e-14: 75.7: 10.65		RHOQ_HUMAN (23-236): 1.99e-73: 223: 50.00
+	Hs
		925766 MRCKB_HUMAN (12-285): 1.02e-11: 67.2: 14.92		RAC1_HUMAN (32-217): 3.34e-76: 230: 53.23
+	Hs
		892702 MRCKB_HUMAN (12-285): 1.02e-11: 67.2: 14.92		RAC3_HUMAN (32-206): 6.17e-74: 224: 56.00
+	Hs
		564758 MRCKB_HUMAN (12-285): 1.02e-11: 67.2: 14.92		RHOQ_HUMAN (23-236): 1.99e-73: 223: 50.00
+	Hs
		545725 MRCKB_HUMAN (12-285): 1.02e-11: 67.2: 14.92		RAC2_HUMAN (32-216): 6.11e-73: 222: 52.43
+	Hs
		901094 MRCKB_HUMAN (12-285): 1.02e-11: 67.2: 14.92		RHOA_HUMAN (33-215): 9.31e-73: 221: 42.62
+	Hs
		894128 MRCKG_HUMAN (3-285): 1.48e-14: 75.7: 10.65		CDC42_HUMAN (32-207): 2.12e-66: 205: 57.39
+	Hs
		894628 MRCKB_HUMAN (12-285): 1.02e-11: 67.2: 14.92		CDC42_HUMAN (32-207): 2.12e-66: 205: 57.39