HitPredict

Interactor 1: TPM3 (P06753)
Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3) (Tropomyosin-5) (hTM5)
Gene: TPM3

Interactor 2: NUF2 (Q9BZD4)
Kinetochore protein Nuf2 (hNuf2) (hNuf2R) (hsNuf2) (Cell division cycle-associated protein 1)
Gene: NUF2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 285 Hs			1 464
+	Mm
		358682 LAMA1_MOUSE (4-280): 3.27e-51: 182: 14.84		LAMB1_MOUSE (147-464): 8.51e-43: 164: 11.71
+	Hs
		433115 LAMB1_HUMAN (7-281): 2.34e-53: 188: 21.56		LAMC1_HUMAN (141-458): 1.63e-27: 118: 13.10
+	Hs
		419054 TPM3_HUMAN (1-285): 3.63e-44: 153: 100.00		MYO5C_HUMAN (129-464): 4.78e-26: 114: 13.30
+	Hs
		434437 TPM2_HUMAN (2-285): 1.42e-39: 141: 86.27		MYO5C_HUMAN (129-464): 4.78e-26: 114: 13.30
+	Hs
		451288 TPM1_HUMAN (2-285): 2.54e-44: 153: 91.20		DLG5_HUMAN (129-454): 3.27e-21: 99.3: 11.01
+	Hs
		148289 TPM3_HUMAN (1-285): 3.63e-44: 153: 100.00		CTRO_HUMAN (134-461): 1.02e-10: 66.5: 12.65
+	Hs
		419011 TPM3_HUMAN (1-285): 3.63e-44: 153: 100.00		MY18A_HUMAN (135-460): 3.25e-09: 61.5: 9.88
+	Hs
		451293 TPM1_HUMAN (2-285): 2.54e-44: 153: 91.20		MY18A_HUMAN (135-460): 3.25e-09: 61.5: 9.88
+	Hs
		434415 TPM2_HUMAN (2-285): 1.42e-39: 141: 86.27		MY18A_HUMAN (135-460): 3.25e-09: 61.5: 9.88
+	Hs
		148661 TPM4_HUMAN (43-285): 1.76e-33: 124: 69.96		CTRO_HUMAN (134-461): 1.02e-10: 66.5: 12.65
+	Hs
		932031 TPM4_HUMAN (43-285): 1.76e-33: 124: 69.96		MY18A_HUMAN (135-460): 3.25e-09: 61.5: 9.88
+	Rn
		1186812 MRCKB_RAT (3-285): 1.56e-12: 69.5: 14.09		MRCKB_RAT (215-462): 3.61e-11: 67.7: 12.10
+	Rn
		222476 MRCKB_RAT (3-285): 1.56e-12: 69.5: 14.09		MRCKA_RAT (115-454): 4.65e-10: 64.2: 11.30
+	Hs
		1137917 MRCKB_HUMAN (12-285): 1.02e-11: 67.2: 14.92		MRCKA_HUMAN (144-454): 3.07e-09: 61.5: 13.25
+	Hs
		1268126 MRCKB_HUMAN (12-285): 1.02e-11: 67.2: 14.92		MY18A_HUMAN (135-460): 3.25e-09: 61.5: 9.88
+	Hs
		110802 H7BYY1_HUMAN (2-228): 1.39e-10: 62.2: 21.37		MY18A_HUMAN (135-460): 3.25e-09: 61.5: 9.88