HitPredict

Interactor 1: ITAV (P06756)
Integrin alpha-V (Vitronectin receptor) (Vitronectin receptor subunit alpha) (CD antigen CD51) [Cleaved into: Integrin alpha-V heavy chain; Integrin alpha-V light chain]
Gene: ITGAV

Interactor 2: ITB5 (P18084)
Integrin beta-5
Gene: ITGB5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 12844492, 1694173
Identification Methods affinity chromatography technology, solid phase assay, chromatography technology
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains FG-GAP~Integrin_beta, I-EGF_1~Integrin_alpha2, Integrin_B_tail~Integrin_alpha2, Integrin_alpha2~Integrin_beta, Integrin_alpha2~PSI_integrin, Integrin_alpha~Integrin_b_cyt
Common GO terms GO:0001618 - virus receptor activity
GO:0005178 - integrin binding
GO:0005886 - plasma membrane
GO:0005925 - focal adhesion
GO:0007160 - cell-matrix adhesion
and 12 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1048
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024