HitPredict

Interactor 1: CATL1 (P07711)
Procathepsin L (EC 3.4.22.15) (Cathepsin L1) (Major excreted protein) (MEP) [Cleaved into: Cathepsin L; Cathepsin L heavy chain; Cathepsin L light chain]
Gene: CTSL

Interactor 2: CATL3 (Q5NE16)
Putative inactive cathepsin L-like protein CTSL3P (Cathepsin L3 pseudogene) (HCTSL-s)
Gene: CTSL3P

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.80	0.637

Property	Details
Experiments	28514442, 33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Inhibitor_I29~Inhibitor_I29, Inhibitor_I29~Peptidase_C1
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 333 Hs			1 218
+	Hs
		245778 CATL1_HUMAN (1-333): 5.35e-176: 492: 100.00		CATL2_HUMAN (1-214): 5.69e-91: 272: 35.04
+	Hs
		429797 CATL1_HUMAN (1-333): 5.35e-176: 492: 100.00		CATL1_HUMAN (1-214): 5.34e-91: 272: 37.18
+	Hs
		429843 CATL1_HUMAN (1-333): 5.35e-176: 492: 100.00		CATK_HUMAN (1-214): 1.83e-79: 242: 24.26
+	Hs
		245797 CATL2_HUMAN (1-333): 1.72e-170: 478: 77.25		CATK_HUMAN (1-214): 1.83e-79: 242: 24.26
+	Hs
		429802 CATL1_HUMAN (1-333): 5.35e-176: 492: 100.00		CATH_HUMAN (2-215): 1.47e-69: 217: 19.83
+	Dm
		1278623 CATL_DROME (20-333): 2.37e-150: 428: 53.54		CPR1_DROME (1-216): 3.12e-66: 216: 19.17
+	Hs
		637213 CATS_HUMAN (1-333): 5.17e-142: 406: 47.77		CATS_HUMAN (1-215): 5.14e-77: 236: 20.76