HitPredict

Interactor 1: CSK2A (P08181)
Casein kinase II subunit alpha (CK II subunit alpha) (EC 2.7.11.1)
Gene: CkIIalpha

Interactor 2: ESM8 (P13098)
Enhancer of split m8 protein (E(spl)m8)
Gene: E(spl)m8-HLH

Species: Drosophila melanogaster

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.676

Property	Details
Experiments	21789514, 15003630, 11208814
Identification Methods	two hybrid, pull down, protein kinase assay
Interaction Type	direct interaction, physical association, phosphorylation reaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0048749 - compound eye development
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 336 Dm			1 179
+	Dm
		437051 CSK2A_DROME (1-336): 2.74e-121: 353: 100.00		ESM7_DROME (3-179): 8.96e-52: 165: 40.86
+	Hs
		934585 CSK21_HUMAN (2-329): 5.21e-121: 355: 88.42		HEY1_HUMAN (1-175): 1.26e-44: 151: 18.46
+	Dm
		437050 CSK2A_DROME (1-336): 2.74e-121: 353: 100.00		ESM5_DROME (2-179): 1.52e-46: 152: 60.00
+	Hs
		146454 CSK22_HUMAN (5-332): 1.47e-129: 375: 81.71		BHE40_HUMAN (7-176): 5.85e-33: 123: 19.25
+	Hs
		934393 CSK21_HUMAN (2-329): 5.21e-121: 355: 88.42		HES6_HUMAN (2-179): 1.65e-42: 143: 18.01
+	Hs
		586966 CSK22_HUMAN (5-332): 1.47e-129: 375: 81.71		BHE41_HUMAN (7-165): 6.85e-31: 118: 17.14
+	Dm
		437054 CSK2A_DROME (1-336): 2.74e-121: 353: 100.00		HAIR_DROME (8-178): 5.25e-38: 134: 24.14
+	Hs
		146478 CSK21_HUMAN (2-329): 5.21e-121: 355: 88.42		BHE40_HUMAN (7-176): 5.85e-33: 123: 19.25
+	Hs
		934457 CSK21_HUMAN (2-329): 5.21e-121: 355: 88.42		BHE41_HUMAN (7-165): 6.85e-31: 118: 17.14
+	Mm
		1141319 CSK21_MOUSE (2-329): 2.71e-121: 355: 88.42		BMAL1_MOUSE (12-79): 1.64e-19: 86.8: 25.00
+	Hs
		126122 CSK21_HUMAN (2-329): 5.21e-121: 355: 88.42		BMAL1_HUMAN (2-79): 1.63e-19: 86.8: 21.80