Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: PSMD4 (P55036)
26S proteasome non-ATPase regulatory subunit 4 (26S proteasome regulatory subunit RPN10) (26S proteasome regulatory subunit S5A) (Antisecretory factor 1) (AF) (ASF) (Multiubiquitin chain-binding protein)
Gene: PSMD4

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 1.00 0.993

The method score is based on:

Property Details
Experiments 8570649, 9488668, 14585839, 16222312, 19796170, 16497222, 23649778, 25633294, 25666615, 28082312, 29966650, 30664872, 32157086, 24361330, 15826667, 12095625, 20542005, 17368669, 16007098, 19240029 and 9 others

more...

Identification Methods pull down, affinity chromatography technology, x-ray crystallography, unspecified method, protein array, far western blotting, surface plasmon resonance
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains UIM~ubiquitin, VWA_2~ubiquitin
Common GO terms GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 685
Hs

1 377
+ Hs
+ At
+ Sc
+ Mm
+ Hs
+ Hs
+ Hs
+ Xl
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024