HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: WDR5 (P61964)
WD repeat-containing protein 5 (BMP2-induced 3-kb gene protein)
Gene: WDR5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.60	0.646

Property	Details
Experiments	32076268, 38803224, 16196087
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 334
+	Hs
		475845 UBC_HUMAN (1-685): 0: 846: 100.00		SMU1_HUMAN (30-331): 7.66e-39: 145: 28.71
+	Hs
		476151 UBC_HUMAN (1-685): 0: 846: 100.00		FBXW7_HUMAN (198-333): 4.06e-28: 116: 30.15
+	Hs
		476181 UBC_HUMAN (1-685): 0: 846: 100.00		SNR40_HUMAN (248-333): 6.9e-13: 70.4: 25.29
+	Hs
		196947 UBC_HUMAN (1-685): 0: 846: 100.00		PRP4_HUMAN (244-333): 1.12e-10: 64.2: 19.39
+	Dm
		477542 UBIQP_DROME (1-610): 0: 752: 99.84		FBXW7_DROME (40-169): 6.72e-18: 86.7: 39.10
+	Hs
		903105 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00
+	Rn
		925834 UBC_RAT (1-108): 1.27e-29: 127: 90.74		LIS1_RAT (2-289): 1.02e-94: 288: 29.49
+	Hs
		397828 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		LIS1_HUMAN (2-289): 1.55e-94: 288: 29.49
+	Mm
		476956 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		PLRG1_MOUSE (2-333): 3.73e-85: 267: 26.12
+	Hs
		475165 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		WDR83_HUMAN (25-333): 8.76e-84: 257: 31.83
+	At
		187391 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		O22826_ARATH (248-333): 3.3e-12: 68.5: 24.14