HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: UB2D3 (P61077)
Ubiquitin-conjugating enzyme E2 D3 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme D3) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme D3) (Ubiquitin carrier protein D3) (Ubiquitin-conjugating enzyme E2(17)KB 3) (Ubiquitin-conjugating enzyme E2-17 kDa 3) (Ubiquitin-protein ligase D3)
Gene: UBE2D3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.978

The method score is based on:

Property Details
Experiments 28190767, 27182664, 34642328, 16196087, 24403071, 17170710, 30631154, 30884854, 30901564, 16543155, 21900206, 24446487
Identification Methods pull down, proximity labelling technology, affinity chromatography technology, enzymatic study, x-ray crystallography, two hybrid, nuclear magnetic resonance
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains UQ_con~ubiquitin
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0010008 - endosome membrane
and 3 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 685
Hs

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Last updated: 15 Jul 2024