HitPredict

Interactor 1: NFL (P08551)
Neurofilament light polypeptide (NF-L) (68 kDa neurofilament protein) (Neurofilament triplet L protein)
Gene: Nefl

Interactor 2: FXR1 (Q61584)
RNA-binding protein FXR1 (FXR1P) (mFxr1p)
Gene: FXR1

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28671696
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0030424 - axon GO:0030426 - growth cone GO:0043005 - neuron projection
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 543 Mm			1 677
+	Hs
		422154 NFL_HUMAN (1-543): 5.08e-148: 437: 91.54		FXR1_HUMAN (1-677): 0: 995: 88.33
+	Mm
		804945 AINX_MOUSE (65-402): 8.64e-90: 286: 56.18		FXR1_MOUSE (1-677): 0: 1073: 100.00
+	Mm
		589631 VIME_MOUSE (69-403): 9.35e-80: 259: 51.94		FXR1_MOUSE (1-677): 0: 1073: 100.00
+	Mm
		440294 NFM_MOUSE (27-481): 2.99e-72: 248: 45.42		FXR1_MOUSE (1-677): 0: 1073: 100.00
+	Hs
		843695 AINX_HUMAN (66-402): 4.62e-92: 292: 58.11		FXR1_HUMAN (1-677): 0: 995: 88.33
+	Hs
		443401 VIME_HUMAN (34-403): 8.22e-83: 267: 50.00		FXR1_HUMAN (1-677): 0: 995: 88.33
+	Hs
		535353 GFAP_HUMAN (66-402): 2.45e-69: 231: 48.37		FXR1_HUMAN (1-677): 0: 995: 88.33
+	Hs
		443402 VIME_HUMAN (34-403): 8.22e-83: 267: 50.00		FXR2_HUMAN (4-656): 0: 851: 64.06
+	Hs
		535354 GFAP_HUMAN (66-402): 2.45e-69: 231: 48.37		FXR2_HUMAN (4-656): 0: 851: 64.06
+	Mm
		804952 AINX_MOUSE (65-402): 8.64e-90: 286: 56.18		Q8BPK8_MOUSE (1-334): 0: 622: 73.65
+	Mm
		440275 NFL_MOUSE (1-543): 1.38e-57: 202: 100.00		Q8BPK8_MOUSE (1-334): 0: 622: 73.65
+	Mm
		729423 AINX_MOUSE (65-402): 8.64e-90: 286: 56.18		FMR1_MOUSE (219-461): 1.28e-49: 184: 42.80
+	Mm
		440263 NFL_MOUSE (1-543): 1.38e-57: 202: 100.00		FMR1_MOUSE (219-461): 1.28e-49: 184: 42.80