Interactor 1: KPCB (P05771)
Protein kinase C beta type (PKC-B) (PKC-beta) (EC 2.7.11.13)
Gene: PRKCB
Interactor 2: BTK (Q06187)
Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell progenitor kinase) (BPK) (Bruton tyrosine kinase)
Gene: BTK
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 1.00 | 0.647 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 12679936 |
| Identification Methods | pull down |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | C1_1~PH, C1_1~PK_Tyr_Ser-Thr, C1_1~SH2, C2~SH2, C2~SH3_1, PH~Pkinase, PK_Tyr_Ser-Thr~Pkinase |
| Common GO terms | GO:0002250 - adaptive immune response GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol and 6 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Last updated: 11Aug2025