HitPredict

Interactor 1: PGFRA (P16234)
Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (CD140a antigen) (Platelet-derived growth factor alpha receptor) (Platelet-derived growth factor receptor 2) (PDGFR-2) (CD antigen CD140a)
Gene: PDGFRA

Interactor 2: ULBP3 (Q9BZM4)
UL16-binding protein 3 (ALCAN-gamma) (NKG2D ligand 3) (N2DL-3) (NKG2DL3) (Retinoic acid early transcript 1N)
Gene: ULBP3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0009897 - external side of plasma membrane
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1089 Hs			1 244
+	Hs
		557247 PGFRA_HUMAN (1-1089): 0: 817: 100.00		ULBP2_HUMAN (3-244): 1.32e-96: 284: 51.02
+	Hs
		382273 PGFRB_HUMAN (29-1089): 0: 650: 43.33		HLAA_HUMAN (8-240): 1.83e-116: 338: 23.21
+	Hs
		382331 FLT3_HUMAN (4-979): 1e-158: 498: 27.84		HLAA_HUMAN (8-240): 1.83e-116: 338: 23.21
+	Hs
		488144 FLT3_HUMAN (4-979): 1e-158: 498: 27.84		HLAC_HUMAN (7-240): 7.71e-110: 322: 21.85
+	Hs
		382306 FGFR2_HUMAN (6-339): 9.02e-49: 189: 14.90		HLAA_HUMAN (8-240): 1.83e-116: 338: 23.21
+	Hs
		382400 TYRO3_HUMAN (33-238): 3.34e-24: 111: 11.56		HLAA_HUMAN (8-240): 1.83e-116: 338: 23.21
+	Hs
		382268 RET_HUMAN (573-690): 7.85e-22: 104: 43.22		HLAA_HUMAN (8-240): 1.83e-116: 338: 23.21
+	Hs
		382308 FGFR4_HUMAN (3-221): 4.21e-22: 104: 8.36		HLAA_HUMAN (8-240): 1.83e-116: 338: 23.21
+	Hs
		382329 VGFR3_HUMAN (128-609): 7.49e-19: 94.9: 11.28		HLAA_HUMAN (8-240): 1.83e-116: 338: 23.21
+	Hs
		382280 FGFR1_HUMAN (3-177): 1.39e-14: 80.7: 10.71		HLAA_HUMAN (8-240): 1.83e-116: 338: 23.21
+	Hs
		382433 NTRK3_HUMAN (28-227): 3.23e-13: 76.1: 9.01		HLAA_HUMAN (8-240): 1.83e-116: 338: 23.21
+	Hs
		169158 MUSK_HUMAN (2-127): 4.82e-12: 72.6: 12.98		HLAB_HUMAN (8-240): 1.81e-113: 331: 22.79
+	Hs
		488237 NTRK3_HUMAN (28-227): 3.23e-13: 76.1: 9.01		HLAC_HUMAN (7-240): 7.71e-110: 322: 21.85
+	Hs
		169162 MUSK_HUMAN (2-127): 4.82e-12: 72.6: 12.98		HLAC_HUMAN (7-240): 7.71e-110: 322: 21.85
+	Hs
		673955 NTRK3_HUMAN (28-227): 3.23e-13: 76.1: 9.01		HLAF_HUMAN (9-240): 1.97e-97: 289: 21.61
+	Hs
		601552 FGFR2_HUMAN (6-339): 9.02e-49: 189: 14.90		RAE1E_HUMAN (31-241): 1.07e-44: 152: 41.23
+	Hs
		508117 FGFR1_HUMAN (3-177): 1.39e-14: 80.7: 10.71		RAE1E_HUMAN (31-241): 1.07e-44: 152: 41.23