HitPredict

Interactor 1: FYN (P06241)
Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like kinase) (SLK) (p59-Fyn)
Gene: FYN

Interactor 2: TNR1A (P19438)
Tumor necrosis factor receptor superfamily member 1A (Tumor necrosis factor receptor 1) (TNF-R1) (Tumor necrosis factor receptor type I) (TNF-RI) (TNFR-I) (p55) (p60) (CD antigen CD120a) [Cleaved into: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)]
Gene: TNFRSF1A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0045121 - membrane raft
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 537 Hs			1 455
+	Hs
		557078 SRC_HUMAN (1-537): 0: 598: 68.21		TNR1A_HUMAN (1-455): 2.08e-147: 429: 100.00
+	Hs
		163223 FYN_HUMAN (1-537): 0: 644: 100.00		TR10B_HUMAN (39-445): 5.55e-78: 251: 20.43
+	Hs
		440379 FYN_HUMAN (1-537): 0: 644: 100.00		TNR6_HUMAN (1-167): 1.19e-46: 165: 23.21
+	Hs
		557105 SRC_HUMAN (1-537): 0: 598: 68.21		TNR6_HUMAN (1-167): 1.19e-46: 165: 23.21
+	Hs
		462989 YES_HUMAN (1-537): 0: 592: 71.61		TNR6_HUMAN (1-167): 1.19e-46: 165: 23.21
+	Mm
		204643 LYN_MOUSE (1-535): 0: 538: 53.92		TNR11_MOUSE (34-368): 2.21e-59: 207: 16.34
+	Mm
		630393 FYN_MOUSE (1-537): 0: 643: 99.44		TNR9_MOUSE (59-227): 4.92e-23: 99.7: 17.75
+	Hs
		439955 LCK_HUMAN (40-535): 0: 552: 57.40		TNR6_HUMAN (1-167): 1.19e-46: 165: 23.21
+	Mm
		440270 LCK_MOUSE (40-535): 0: 555: 57.00		TNR9_MOUSE (59-227): 4.92e-23: 99.7: 17.75
+	Mm
		693154 BTK_MOUSE (1-531): 7.98e-155: 458: 33.52		TNR5_MOUSE (43-326): 7.34e-53: 180: 20.63
+	Hs
		675004 BTK_HUMAN (4-531): 8e-154: 456: 30.91		TNR6_HUMAN (1-167): 1.19e-46: 165: 23.21