HitPredict

Interactor 1: PGFRA (P16234)
Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (CD140a antigen) (Platelet-derived growth factor alpha receptor) (Platelet-derived growth factor receptor 2) (PDGFR-2) (CD antigen CD140a)
Gene: PDGFRA

Interactor 2: LAMB2 (P55268)
Laminin subunit beta-2 (Laminin B1s chain) (Laminin-11 subunit beta) (Laminin-14 subunit beta) (Laminin-15 subunit beta) (Laminin-3 subunit beta) (Laminin-4 subunit beta) (Laminin-7 subunit beta) (Laminin-9 subunit beta) (S-laminin subunit beta) (S-LAM beta)
Gene: LAMB2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 1089 Hs			1 1798
+	Hs
		433118 PGFRA_HUMAN (1-1089): 0: 817: 100.00		LAMB1_HUMAN (874-1798): 1.4e-42: 173: 14.84
+	Hs
		557121 PGFRA_HUMAN (1-1089): 0: 817: 100.00		LAMB3_HUMAN (458-770): 1.53e-12: 75.3: 12.02
+	Hs
		172642 PGFRA_HUMAN (1-1089): 0: 817: 100.00		LAMA5_HUMAN (561-809): 2.08e-11: 71.9: 10.36
+	Hs
		557037 PGFRA_HUMAN (1-1089): 0: 817: 100.00		LAMA1_HUMAN (541-742): 5.94e-10: 66.9: 9.80
+	Hs
		317784 PGFRA_HUMAN (1-1089): 0: 817: 100.00		NET1_HUMAN (782-952): 7.93e-10: 65.7: 21.11
+	Hs
		980386 NTRK2_HUMAN (48-776): 2.93e-51: 197: 14.04		NOTC2_HUMAN (295-686): 1.81e-25: 118: 13.07
+	Hs
		434309 RET_HUMAN (573-690): 7.85e-22: 104: 43.22		NOTC3_HUMAN (261-926): 5.12e-44: 178: 13.97
+	Dr
		94564 FGFR4_DANRE (34-411): 2.34e-50: 195: 12.65		F1QUK5_DANRE (670-859): 2.86e-09: 64.2: 14.57
+	Dm
		1098520 Q8IPG1_DROME (20-534): 3.76e-43: 173: 16.61		NETB_DROME (1065-1190): 7.71e-11: 69.3: 29.73
+	Hs
		434176 RET_HUMAN (573-690): 7.85e-22: 104: 43.22		NOTC2_HUMAN (295-686): 1.81e-25: 118: 13.07
+	Hs
		607947 FGFR4_HUMAN (3-221): 4.21e-22: 104: 8.36		NOTC2_HUMAN (295-686): 1.81e-25: 118: 13.07
+	Hs
		729266 VGFR3_HUMAN (128-609): 7.49e-19: 94.9: 11.28		NOTC2_HUMAN (295-686): 1.81e-25: 118: 13.07
+	Hs
		980385 NTRK3_HUMAN (28-227): 3.23e-13: 76.1: 9.01		NOTC2_HUMAN (295-686): 1.81e-25: 118: 13.07
+	Dm
		1098433 PTK7_DROME (131-637): 1.77e-26: 119: 13.24		NETB_DROME (1065-1190): 7.71e-11: 69.3: 29.73