HitPredict

Interactor 1: PTK7 (Q13308)
Inactive tyrosine-protein kinase 7 (Colon carcinoma kinase 4) (CCK-4) (Protein-tyrosine kinase 7) (Pseudo tyrosine kinase receptor 7) (Tyrosine-protein kinase-like 7)
Gene: PTK7

Interactor 2: CEA21 (Q3KPI0)
Cell adhesion molecule CEACAM21 (Carcinoembryonic antigen-related cell adhesion molecule 21) (CEA cell adhesion molecule 21)
Gene: CEACAM21

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	26186194
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	I-set~Ig_3, I-set~V-set, Ig_3~Ig_3, Ig_3~V-set
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1070 Hs			1 293
+	Dr
		68489 VGFR4_DANRE (10-1068): 1.86e-170: 537: 19.20		A8DZ85_DANRE (2-244): 1.4e-39: 149: 19.36
+	Hs
		773347 TIE1_HUMAN (55-1069): 1.32e-152: 485: 17.38		PSG5_HUMAN (2-242): 9.92e-25: 103: 15.73
+	Hs
		1439191 ROBO2_HUMAN (1-810): 9.04e-106: 363: 15.91		ROBO2_HUMAN (3-250): 4.73e-41: 153: 16.54
+	Hs
		1439198 ROBO2_HUMAN (1-810): 9.04e-106: 363: 15.91		ROBO1_HUMAN (138-282): 6.62e-22: 97.6: 16.56
+	Hs
		541521 FGFR1_HUMAN (2-231): 1.1e-34: 145: 12.77		CEA21_HUMAN (1-293): 1.94e-71: 223: 100.00
+	Hs
		1439197 ALK_HUMAN (695-1067): 1.22e-52: 204: 32.90		ROBO2_HUMAN (3-250): 4.73e-41: 153: 16.54
+	Hs
		412363 NTRK1_HUMAN (555-1061): 3.11e-57: 214: 30.31		PXDN_HUMAN (121-290): 1.32e-29: 120: 17.61
+	Hs
		71378 FGFR1_HUMAN (2-231): 1.1e-34: 145: 12.77		HECA2_HUMAN (25-292): 5.11e-47: 165: 20.62
+	Dm
		1174395 ROR1_DROME (790-1061): 1.62e-57: 213: 39.42		PTK7_DROME (80-286): 4.77e-19: 89: 21.83
+	Hs
		1462024 ALK_HUMAN (695-1067): 1.22e-52: 204: 32.90		ROBO1_HUMAN (138-282): 6.62e-22: 97.6: 16.56
+	Hs
		731840 PTK7_HUMAN (2-329): 4.58e-53: 204: 19.94		CEAM8_HUMAN (12-260): 1.23e-19: 89.1: 14.62
+	Hs
		1153027 ALK_HUMAN (695-1067): 1.22e-52: 204: 32.90		MYLK_HUMAN (30-140): 1.84e-12: 69.5: 11.71
+	Hs
		412342 NTRK1_HUMAN (555-1061): 3.11e-57: 214: 30.31		TITIN_HUMAN (152-259): 8.53e-09: 58.7: 16.22
+	Hs
		249220 DSCAM_HUMAN (2-809): 5.46e-28: 124: 11.76		ROBO1_HUMAN (138-282): 6.62e-22: 97.6: 16.56
+	Hs
		609946 VGFR1_HUMAN (225-713): 1.12e-34: 146: 16.99		VGFR1_HUMAN (40-240): 1.13e-13: 73.2: 15.42
+	Mm
		999933 DSCAM_MOUSE (2-809): 7.34e-29: 127: 11.87		DCC_MOUSE (3-266): 8.05e-18: 85.6: 9.35
+	Hs
		648757 FGFR4_HUMAN (2-127): 4.45e-13: 75.8: 17.02		ROBO1_HUMAN (138-282): 6.62e-22: 97.6: 16.56
+	Mm
		1222168 MUSK_MOUSE (130-422): 3.42e-12: 72.8: 22.59		MUSK_MOUSE (139-278): 1.09e-21: 96.8: 16.20
+	Dm
		1230945 PTK7_DROME (34-247): 8.53e-13: 75.1: 24.20		PTK7_DROME (80-286): 4.77e-19: 89: 21.83
+	Hs
		1361879 TITIN_HUMAN (599-828): 3.2e-10: 67: 15.25		TITIN_HUMAN (152-259): 8.53e-09: 58.7: 16.22