HitPredict

Interactor 1: TPM3 (P06753)
Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3) (Tropomyosin-5) (hTM5)
Gene: TPM3

Interactor 2: RHBT2 (Q9BYZ6)
Rho-related BTB domain-containing protein 2 (Deleted in breast cancer 2 gene protein) (p83)
Gene: RHOBTB2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005856 - cytoskeleton GO:0007015 - actin filament organization
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 285 Hs			1 727
+	Hs
		482961 TPM1_HUMAN (2-285): 1.36e-44: 154: 91.20		RHBT2_HUMAN (1-705): 2.12e-178: 529: 100.00
+	Hs
		464207 TPM2_HUMAN (2-285): 1.41e-40: 143: 86.27		RHBT2_HUMAN (1-705): 2.12e-178: 529: 100.00
+	Hs
		995472 TPM4_HUMAN (43-285): 3.76e-34: 126: 69.96		RHBT2_HUMAN (1-705): 2.12e-178: 529: 100.00
+	Hs
		318577 TPM3_HUMAN (1-285): 1.29e-44: 154: 100.00		RHBT1_HUMAN (1-708): 7.61e-161: 482: 67.65
+	Hs
		318719 TPM4_HUMAN (43-285): 3.76e-34: 126: 69.96		RHBT1_HUMAN (1-708): 7.61e-161: 482: 67.65
+	Hs
		482869 TPM1_HUMAN (2-285): 1.36e-44: 154: 91.20		CDC42_HUMAN (12-218): 7.12e-92: 286: 36.67
+	Hs
		464185 TPM2_HUMAN (2-285): 1.41e-40: 143: 86.27		ABTB2_HUMAN (231-647): 1.53e-77: 270: 17.08
+	Hs
		447737 TPM3_HUMAN (1-285): 1.29e-44: 154: 100.00		RHOG_HUMAN (12-218): 7.1e-71: 231: 36.19
+	Hs
		988262 TPM4_HUMAN (43-285): 3.76e-34: 126: 69.96		RAC1_HUMAN (12-220): 5.14e-72: 234: 35.38
+	Hs
		995404 TPM4_HUMAN (43-285): 3.76e-34: 126: 69.96		RHOG_HUMAN (12-218): 7.1e-71: 231: 36.19
+	Hs
		976630 EP15R_HUMAN (155-285): 8.49e-10: 61.1: 20.61		RB11A_HUMAN (5-252): 7.95e-71: 232: 16.34