HitPredict

Interactor 1: RHBT1 (O94844)
Rho-related BTB domain-containing protein 1
Gene: RHOBTB1

Interactor 2: TPM4 (P67936)
Tropomyosin alpha-4 chain (TM30p1) (Tropomyosin-4)
Gene: TPM4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	31871319, 37575477
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005856 - cytoskeleton GO:0007015 - actin filament organization
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 696 Hs			1 248
+	Hs
		318577 RHBT1_HUMAN (1-696): 0: 538: 100.00		TPM3_HUMAN (4-248): 6.5e-47: 159: 69.39
+	Hs
		482961 RHBT2_HUMAN (1-690): 4.26e-168: 501: 67.94		TPM1_HUMAN (4-248): 1.44e-48: 163: 68.16
+	Hs
		447853 RHBT2_HUMAN (1-690): 4.26e-168: 501: 67.94		TPM3_HUMAN (4-248): 6.5e-47: 159: 69.39
+	Hs
		995472 RHBT2_HUMAN (1-690): 4.26e-168: 501: 67.94		TPM4_HUMAN (1-248): 5.58e-47: 158: 100.00
+	Hs
		464207 RHBT2_HUMAN (1-690): 4.26e-168: 501: 67.94		TPM2_HUMAN (4-248): 5.06e-42: 146: 69.39
+	Hs
		482869 CDC42_HUMAN (12-218): 1.56e-89: 279: 37.14		TPM1_HUMAN (4-248): 1.44e-48: 163: 68.16
+	Mm
		878597 CDC42_MOUSE (12-218): 1.56e-89: 279: 37.14		CTRO_MOUSE (4-247): 3.98e-40: 148: 20.65
+	Hs
		988262 RAC1_HUMAN (12-219): 3.84e-73: 236: 35.55		TPM4_HUMAN (1-248): 5.58e-47: 158: 100.00
+	Hs
		447737 RHOG_HUMAN (12-210): 1.95e-69: 226: 36.63		TPM3_HUMAN (4-248): 6.5e-47: 159: 69.39
+	Mm
		878598 RAC1_MOUSE (12-219): 3.84e-73: 236: 35.55		CTRO_MOUSE (4-247): 3.98e-40: 148: 20.65
+	Hs
		995404 RHOG_HUMAN (12-210): 1.95e-69: 226: 36.63		TPM4_HUMAN (1-248): 5.58e-47: 158: 100.00
+	Mm
		878608 RHOA_MOUSE (16-215): 1.75e-68: 224: 36.45		CTRO_MOUSE (4-247): 3.98e-40: 148: 20.65
+	Rn
		97301 RHOA_RAT (16-215): 1.75e-68: 224: 36.45		CTRO_RAT (4-247): 4.49e-39: 146: 20.24