HitPredict

Interactor 1: TPM1 (P09493)
Tropomyosin alpha-1 chain (Alpha-tropomyosin) (Tropomyosin-1)
Gene: TPM1

Interactor 2: RHBT2 (Q9BYZ6)
Rho-related BTB domain-containing protein 2 (Deleted in breast cancer 2 gene protein) (p83)
Gene: RHOBTB2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005856 - cytoskeleton GO:0007015 - actin filament organization GO:0008360 - regulation of cell shape
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 284 Hs			1 727
+	Hs
		447853 TPM3_HUMAN (1-284): 1.02e-43: 152: 91.20		RHBT2_HUMAN (1-705): 2.12e-178: 529: 100.00
+	Hs
		464207 TPM2_HUMAN (1-284): 1.4e-38: 138: 85.56		RHBT2_HUMAN (1-705): 2.12e-178: 529: 100.00
+	Hs
		995472 TPM4_HUMAN (42-284): 3.78e-33: 123: 68.72		RHBT2_HUMAN (1-705): 2.12e-178: 529: 100.00
+	Hs
		318577 TPM3_HUMAN (1-284): 1.02e-43: 152: 91.20		RHBT1_HUMAN (1-708): 7.61e-161: 482: 67.65
+	Hs
		318719 TPM4_HUMAN (42-284): 3.78e-33: 123: 68.72		RHBT1_HUMAN (1-708): 7.61e-161: 482: 67.65
+	Hs
		482869 TPM1_HUMAN (1-284): 2.36e-44: 153: 100.00		CDC42_HUMAN (12-218): 7.12e-92: 286: 36.67
+	Hs
		955277 MRCKA_HUMAN (1-282): 1.09e-31: 126: 17.67		CDC42_HUMAN (12-218): 7.12e-92: 286: 36.67
+	Hs
		464185 TPM2_HUMAN (1-284): 1.4e-38: 138: 85.56		ABTB2_HUMAN (231-647): 1.53e-77: 270: 17.08
+	Hs
		601324 MRCKA_HUMAN (1-282): 1.09e-31: 126: 17.67		RHOQ_HUMAN (10-225): 1.25e-84: 267: 36.53
+	Hs
		447737 TPM3_HUMAN (1-284): 1.02e-43: 152: 91.20		RHOG_HUMAN (12-218): 7.1e-71: 231: 36.19
+	Hs
		581101 MRCKA_HUMAN (1-282): 1.09e-31: 126: 17.67		RAC2_HUMAN (12-219): 9.89e-73: 236: 36.97
+	Hs
		953499 MRCKA_HUMAN (1-282): 1.09e-31: 126: 17.67		RAC3_HUMAN (12-208): 3.83e-72: 234: 39.50
+	Hs
		988432 MRCKA_HUMAN (1-282): 1.09e-31: 126: 17.67		RAC1_HUMAN (12-220): 5.14e-72: 234: 35.38
+	Hs
		976324 MRCKA_HUMAN (1-282): 1.09e-31: 126: 17.67		RB11A_HUMAN (5-252): 7.95e-71: 232: 16.34
+	Hs
		1015512 MRCKA_HUMAN (1-282): 1.09e-31: 126: 17.67		RHOG_HUMAN (12-218): 7.1e-71: 231: 36.19
+	Hs
		988262 TPM4_HUMAN (42-284): 3.78e-33: 123: 68.72		RAC1_HUMAN (12-220): 5.14e-72: 234: 35.38
+	Hs
		962148 MRCKA_HUMAN (1-282): 1.09e-31: 126: 17.67		RHOA_HUMAN (16-216): 1.77e-70: 230: 35.29
+	Hs
		995404 TPM4_HUMAN (42-284): 3.78e-33: 123: 68.72		RHOG_HUMAN (12-218): 7.1e-71: 231: 36.19