HitPredict

Interactor 1: NFM (P07197)
Neurofilament medium polypeptide (NF-M) (160 kDa neurofilament protein) (Neurofilament 3) (Neurofilament triplet M protein)
Gene: NEFM

Interactor 2: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0008017 - microtubule binding GO:0030424 - axon GO:0097418 - neurofibrillary tangle
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 916 Hs			1 758
+	Hs
		529875 AINX_HUMAN (8-494): 2.99e-91: 300: 47.69		TAU_HUMAN (1-758): 6.41e-90: 300: 100.00
+	Hs
		528977 K2C5_HUMAN (67-411): 1.1e-88: 296: 29.60		TAU_HUMAN (1-758): 6.41e-90: 300: 100.00
+	Hs
		385225 K2C6A_HUMAN (67-413): 1.68e-88: 295: 30.29		TAU_HUMAN (1-758): 6.41e-90: 300: 100.00
+	Hs
		474431 VIME_HUMAN (8-413): 1.86e-77: 261: 44.61		TAU_HUMAN (1-758): 6.41e-90: 300: 100.00
+	Rn
		619991 AINX_RAT (8-494): 7.24e-89: 293: 48.10		TAU_RAT (1-758): 3.21e-76: 263: 72.11
+	Rn
		98682 AINX_RAT (8-494): 7.24e-89: 293: 48.10		F1LST4_RAT (1-757): 7.75e-76: 262: 72.21
+	Hs
		451107 NFL_HUMAN (74-420): 2.21e-73: 253: 53.16		TAU_HUMAN (1-758): 6.41e-90: 300: 100.00
+	Hs
		528984 GFAP_HUMAN (94-413): 1.97e-67: 233: 48.44		TAU_HUMAN (1-758): 6.41e-90: 300: 100.00
+	Rn
		619988 NFL_RAT (74-420): 1.75e-73: 253: 53.16		TAU_RAT (1-758): 3.21e-76: 263: 72.11
+	Rn
		98679 NFL_RAT (74-420): 1.75e-73: 253: 53.16		F1LST4_RAT (1-757): 7.75e-76: 262: 72.21
+	Mm
		399475 GFAP_MOUSE (65-413): 7.47e-65: 226: 45.56		TAU_MOUSE (1-758): 8.57e-72: 250: 70.17
+	Mm
		470789 NFM_MOUSE (1-734): 2.25e-61: 226: 71.16		TAU_MOUSE (1-758): 8.57e-72: 250: 70.17
+	Hs
		551616 AINX_HUMAN (8-494): 2.99e-91: 300: 47.69		NFH_HUMAN (113-708): 1.12e-25: 115: 10.96
+	Hs
		451109 NFL_HUMAN (74-420): 2.21e-73: 253: 53.16		MTAP2_HUMAN (16-758): 7.48e-30: 129: 23.42
+	Hs
		451110 NFL_HUMAN (74-420): 2.21e-73: 253: 53.16		NFH_HUMAN (113-708): 1.12e-25: 115: 10.96
+	Rn
		599260 NFL_RAT (74-420): 1.75e-73: 253: 53.16		NFH_RAT (63-708): 7.38e-24: 110: 11.23
+	Hs
		451320 NFM_HUMAN (1-916): 8.69e-65: 237: 100.00		NFH_HUMAN (113-708): 1.12e-25: 115: 10.96
+	Hs
		215895 VIME_HUMAN (8-413): 1.86e-77: 261: 44.61		SYNJ1_HUMAN (173-636): 8.49e-14: 77.6: 14.41
+	Hs
		474915 VIME_HUMAN (8-413): 1.86e-77: 261: 44.61		CIC_HUMAN (10-717): 9.83e-10: 64.7: 8.46
+	Hs
		1294691 K2C73_HUMAN (2-415): 1.66e-63: 225: 29.91		CIC_HUMAN (10-717): 9.83e-10: 64.7: 8.46