HitPredict

Interactor 1: CLCA (P09496)
Clathrin light chain A (Lca)
Gene: CLTA

Interactor 2: MPRI (P11717)
Cation-independent mannose-6-phosphate receptor (CI Man-6-P receptor) (CI-MPR) (M6PR) (300 kDa mannose 6-phosphate receptor) (MPR 300) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (CD antigen CD222)
Gene: IGF2R

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	34079125, 35271311
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane GO:0030118 - clathrin coat GO:0032588 - trans-Golgi network membrane
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 248 Hs			1 2491
+	Hs
		451635 CLCB_HUMAN (35-247): 1.52e-67: 210: 60.28		MPRI_HUMAN (1-2491): 0: 4161: 100.00
+	Hs
		362727 CLCA_HUMAN (1-248): 1.53e-98: 289: 100.00		FINC_HUMAN (1769-2040): 1.28e-16: 89.5: 14.63
+	Hs
		362728 CLCB_HUMAN (35-247): 1.52e-67: 210: 60.28		FINC_HUMAN (1769-2040): 1.28e-16: 89.5: 14.63