HitPredict

Interactor 1: HS90A (P07901)
Heat shock protein HSP 90-alpha (EC 3.6.4.10) (Heat shock 86 kDa) (HSP 86) (HSP86) (Tumor-specific transplantation 86 kDa antigen) (TSTA)
Gene: Hsp90aa1

Interactor 2: WDTC1 (Q80ZK9)
WD and tetratricopeptide repeats protein 1
Gene: WDTC1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27113764
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0042826 - histone deacetylase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 733 Mm			1 677
+	Hs
		468594 HS90B_HUMAN (19-733): 0: 1046: 85.59		WDTC1_HUMAN (1-677): 1.07e-127: 394: 96.90
+	Hs
		462043 HS90A_HUMAN (1-733): 0: 1076: 98.23		CHIP_HUMAN (356-482): 3.91e-38: 145: 32.28
+	Hs
		226672 HS90A_HUMAN (1-733): 0: 1076: 98.23		SGTA_HUMAN (326-464): 1.61e-35: 138: 26.76
+	Hs
		117618 K9JA46_HUMAN (1-733): 0: 1076: 98.23		PPP5_HUMAN (346-513): 4.03e-33: 135: 28.26
+	Hs
		461300 HS90A_HUMAN (1-733): 0: 1076: 98.23		PPP5_HUMAN (346-513): 4.03e-33: 135: 28.26
+	Mm
		547287 HS90B_MOUSE (19-733): 0: 1051: 86.15		CHIP_MOUSE (356-482): 2.35e-37: 143: 30.71
+	Hs
		468915 HS90B_HUMAN (19-733): 0: 1046: 85.59		CHIP_HUMAN (356-482): 3.91e-38: 145: 32.28
+	Hs
		226675 HS90B_HUMAN (19-733): 0: 1046: 85.59		SGTA_HUMAN (326-464): 1.61e-35: 138: 26.76
+	Hs
		468210 HS90B_HUMAN (19-733): 0: 1046: 85.59		PPP5_HUMAN (346-513): 4.03e-33: 135: 28.26
+	Hs
		461248 HS90A_HUMAN (1-733): 0: 1076: 98.23		LIS1_HUMAN (514-674): 5.38e-18: 88.7: 15.57
+	Hs
		161692 HS90A_HUMAN (1-733): 0: 1076: 98.23		APAF_HUMAN (535-672): 1.42e-14: 79.9: 15.75
+	Hs
		468239 HS90B_HUMAN (19-733): 0: 1046: 85.59		WDR5_HUMAN (385-673): 1.76e-18: 89.1: 11.26
+	Hs
		468157 HS90B_HUMAN (19-733): 0: 1046: 85.59		LIS1_HUMAN (514-674): 5.38e-18: 88.7: 15.57
+	Cr
		68530 A8J1U1_CHLRE (12-733): 0: 998: 67.63		MUT11_CHLRE (447-610): 4.29e-11: 67.2: 18.50
+	At
		146182 HS904_ARATH (15-733): 0: 984: 68.28		OE64C_ARATH (362-437): 1.69e-09: 62.8: 42.11
+	At
		938321 HS902_ARATH (15-733): 0: 979: 68.28		OE64C_ARATH (362-437): 1.69e-09: 62.8: 42.11
+	At
		690692 HS901_ARATH (15-733): 0: 978: 68.98		OE64C_ARATH (362-437): 1.69e-09: 62.8: 42.11
+	Hs
		161694 ENPL_HUMAN (14-702): 0: 889: 46.43		APAF_HUMAN (535-672): 1.42e-14: 79.9: 15.75
+	Sc
		392158 HSP82_YEAST (16-733): 0: 899: 60.56		STI1_YEAST (358-470): 6.25e-09: 61.2: 32.74
+	Sc
		578768 HSC82_YEAST (16-733): 0: 897: 59.44		STI1_YEAST (358-470): 6.25e-09: 61.2: 32.74