HitPredict

Interactor 1: SGTA (O43765)
Small glutamine-rich tetratricopeptide repeat-containing protein alpha (Alpha-SGT) (Vpu-binding protein) (UBP)
Gene: SGTA

Interactor 2: HS90B (P08238)
Heat shock protein HSP 90-beta (HSP 90) (Heat shock 84 kDa) (HSP 84) (HSP84) (Heat shock protein family C member 3)
Gene: HSP90AB1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	21988832
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	HSP90~TPR_1, HSP90~TPR_8
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 313 Hs			1 724
+	Hs
		226672 SGTA_HUMAN (1-313): 4.33e-68: 216: 100.00		HS90A_HUMAN (1-724): 0: 1069: 85.25
+	Hs
		468915 CHIP_HUMAN (66-229): 1.8e-41: 147: 27.22		HS90B_HUMAN (1-724): 0: 1083: 100.00
+	Mm
		547287 CHIP_MOUSE (66-229): 4.35e-40: 143: 26.04		HS90B_MOUSE (1-724): 0: 1086: 99.59
+	Hs
		462043 CHIP_HUMAN (66-229): 1.8e-41: 147: 27.22		HS90A_HUMAN (1-724): 0: 1069: 85.25
+	Hs
		117618 PPP5_HUMAN (66-268): 8.29e-37: 139: 24.63		K9JA46_HUMAN (1-724): 0: 1069: 85.25
+	Hs
		461300 PPP5_HUMAN (66-268): 8.29e-37: 139: 24.63		HS90A_HUMAN (1-724): 0: 1069: 85.25
+	Mm
		462098 FKBP4_MOUSE (21-261): 1.98e-38: 143: 15.95		HS90A_MOUSE (1-724): 0: 1065: 84.31
+	Dm
		391907 Q9V3E9_DROME (83-226): 4.38e-40: 148: 30.56		HSP83_DROME (10-724): 0: 1053: 78.46
+	At
		103772 OE64M_ARATH (45-206): 1.51e-40: 151: 34.57		HS904_ARATH (10-724): 0: 1004: 66.85
+	At
		146182 OE64C_ARATH (45-204): 1.52e-39: 148: 30.00		HS904_ARATH (10-724): 0: 1004: 66.85
+	At
		103776 OE64M_ARATH (45-206): 1.51e-40: 151: 34.57		HS902_ARATH (10-724): 0: 999: 66.85
+	At
		103774 OE64M_ARATH (45-206): 1.51e-40: 151: 34.57		HS901_ARATH (10-724): 0: 996: 67.97
+	At
		938321 OE64C_ARATH (45-204): 1.52e-39: 148: 30.00		HS902_ARATH (10-724): 0: 999: 66.85
+	At
		690692 OE64C_ARATH (45-204): 1.52e-39: 148: 30.00		HS901_ARATH (10-724): 0: 996: 67.97
+	Hs
		573618 SGTB_HUMAN (1-311): 1.35e-54: 181: 57.24		ENPL_HUMAN (3-693): 0: 914: 46.44
+	Sc
		393503 SGT2_YEAST (2-298): 5.31e-38: 139: 28.45		HSP82_YEAST (12-724): 0: 925: 61.26
+	Sc
		580231 SGT2_YEAST (2-298): 5.31e-38: 139: 28.45		HSC82_YEAST (13-724): 0: 920: 60.22
+	Zm
		33380 A0A1D6L1L3_MAIZE (45-195): 6.81e-41: 151: 33.78		A0A1D6LMW9_MAIZE (5-693): 0: 849: 46.66
+	Dm
		1463394 Q9V3E9_DROME (83-226): 4.38e-40: 148: 30.56		Q9VAY2_DROME (4-692): 0: 845: 46.14
+	Hs
		1245571 Q9BPW0_HUMAN (66-268): 2.2e-37: 140: 24.63		Q6PK50_HUMAN (1-350): 0: 618: 99.71