Interactor 1: SYS (P0A8L1)
Serine--tRNA ligase (EC 6.1.1.11) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase)
Gene: serS

Interactor 2: SYS (P0A8L1)
Serine--tRNA ligase (EC 6.1.1.11) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase)
Gene: serS

Species: Escherichia coli K-12

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.72 1.00 0.850

The method score is based on:

Property Details
Experiments 24561554, unassigned104, 16858726
Identification Methods two hybrid, comigration in non denaturing gel electrophoresis, blue native page, two hybrid array
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Seryl_tRNA_N~Seryl_tRNA_N, Seryl_tRNA_N~tRNA-synt_2b, tRNA-synt_2b~tRNA-synt_2b
Common GO terms GO:0000287 - magnesium ion binding
GO:0004828 - serine-tRNA ligase activity
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0006434 - seryl-tRNA aminoacylation
and 1 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 430
Ec

1 430
+ Hs
+ Hs
+ Hs
+ Ca
+ Cj
+ Hs
+ Sc
+ Dm
+ Sc
+ Hs
+ Pf
+ Ec
+ Hp

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Last updated: 15 Jul 2024