HitPredict

Interactor 1: CXB1 (P08034)
Gap junction beta-1 protein (Connexin-32) (Cx32) (GAP junction 28 kDa liver protein)
Gene: GJB1

Interactor 2: RON (Q04912)
Macrophage-stimulating protein receptor (MSP receptor) (EC 2.7.10.1) (CDw136) (Protein-tyrosine kinase 8) (p185-Ron) (CD antigen CD136) [Cleaved into: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain]
Gene: MST1R

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	30401746
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007399 - nervous system development
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 283 Hs			1 1400
+	Hs
		471979 CXA1_HUMAN (2-227): 4.53e-108: 320: 42.45		MET_HUMAN (1-1391): 0: 1071: 32.30
+	Hs
		464685 CXB1_HUMAN (1-283): 6.7e-161: 450: 100.00		EPHB1_HUMAN (557-1377): 1.9e-170: 537: 17.53
+	Hs
		464675 CXB1_HUMAN (1-283): 6.7e-161: 450: 100.00		EPHA1_HUMAN (727-1375): 1.37e-133: 438: 23.79
+	Hs
		603906 CXA1_HUMAN (2-227): 4.53e-108: 320: 42.45		EPHA4_HUMAN (557-1381): 3.13e-175: 550: 17.21
+	Hs
		603849 CXA1_HUMAN (2-227): 4.53e-108: 320: 42.45		EPHA3_HUMAN (614-1375): 1.13e-170: 537: 17.07
+	Hs
		603905 CXA1_HUMAN (2-227): 4.53e-108: 320: 42.45		EPHB3_HUMAN (557-1377): 6.29e-164: 520: 16.86
+	Hs
		603848 CXA1_HUMAN (2-227): 4.53e-108: 320: 42.45		EPHA2_HUMAN (557-1375): 4.82e-160: 509: 16.67
+	Hs
		710312 CXB7_HUMAN (1-216): 3.76e-100: 293: 48.15		EPHA2_HUMAN (557-1375): 4.82e-160: 509: 16.67
+	Hs
		1147373 CXD3_HUMAN (2-223): 2.51e-90: 271: 38.74		EPHA7_HUMAN (557-1375): 2.24e-167: 529: 18.09
+	Hs
		931815 CXD3_HUMAN (2-223): 2.51e-90: 271: 38.74		EPHB3_HUMAN (557-1377): 6.29e-164: 520: 16.86
+	Hs
		710357 CXD3_HUMAN (2-223): 2.51e-90: 271: 38.74		EPHA2_HUMAN (557-1375): 4.82e-160: 509: 16.67
+	Hs
		541394 CXA8_HUMAN (2-277): 3.9e-117: 344: 40.14		FGFR1_HUMAN (767-1397): 1.17e-113: 379: 22.74
+	Hs
		465397 CXA1_HUMAN (2-227): 4.53e-108: 320: 42.45		IGF1R_HUMAN (1072-1343): 3.58e-52: 204: 37.93
+	Hs
		439633 CXA1_HUMAN (2-227): 4.53e-108: 320: 42.45		INSR_HUMAN (1073-1338): 8.51e-51: 199: 38.73
+	Hs
		603868 CXA1_HUMAN (2-227): 4.53e-108: 320: 42.45		CSK_HUMAN (1086-1344): 9.76e-51: 188: 40.00
+	Rn
		465123 CXA1_RAT (2-227): 5.63e-108: 319: 42.86		CSK_RAT (1086-1344): 9.49e-51: 188: 40.39
+	Hs
		463592 CXB7_HUMAN (1-216): 3.76e-100: 293: 48.15		LYN_HUMAN (1088-1357): 6.9e-51: 190: 39.11
+	Hs
		439784 CXD3_HUMAN (2-223): 2.51e-90: 271: 38.74		INSR_HUMAN (1073-1338): 8.51e-51: 199: 38.73
+	Hs
		463643 CXD3_HUMAN (2-223): 2.51e-90: 271: 38.74		LYN_HUMAN (1088-1357): 6.9e-51: 190: 39.11