Interactor 1: ACRA (P0AE06)
Multidrug efflux pump subunit AcrA (AcrAB-TolC multidrug efflux pump subunit AcrA) (Acridine resistance protein A)
Gene: ACRA
Interactor 2: ACRB (P31224)
Multidrug efflux pump subunit AcrB (AcrAB-TolC multidrug efflux pump subunit AcrB) (Acridine resistance protein B)
Gene: ACRB
Species: Escherichia coli K-12
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 10920254 |
| Identification Methods | anti tag coimmunoprecipitation |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | ACR_tran~CusB_dom_1, ACR_tran~HlyD_D23 |
| Common GO terms | GO:0030288 - outer membrane-bounded periplasmic space GO:0098567 - periplasmic side of plasma membrane GO:0140330 - xenobiotic detoxification by transmembrane export across the cell outer membrane GO:1990281 - efflux pump complex |
| Homologous interactions | 2 |
Homologous interactions
Color coding for hit scores 
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| + | Pa |   |
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| + | Ec |  |
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
