HitPredict

Interactor 1: HS90B (P08238)
Heat shock protein HSP 90-beta (HSP 90) (Heat shock 84 kDa) (HSP 84) (HSP84) (Heat shock protein family C member 3)
Gene: HSP90AB1

Interactor 2: Z3H7B (Q9UGR2)
Zinc finger CCCH domain-containing protein 7B (Rotavirus 'X'-associated non-structural protein) (RoXaN)
Gene: ZC3H7B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	22939624
Identification Methods	luminescence based mammalian interactome mapping
Interaction Type	physical association

Property	Details
Interacting Pfam domains	HSP90~TPR_8
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 724 Hs			1 977
+	Hs
		468809 HS90B_HUMAN (1-724): 0: 1083: 100.00		RPAP3_HUMAN (1-464): 4.28e-61: 222: 15.77
+	Hs
		468798 HS90B_HUMAN (1-724): 0: 1083: 100.00		UN45A_HUMAN (22-200): 1.37e-43: 173: 28.57
+	Hs
		468575 HS90B_HUMAN (1-724): 0: 1083: 100.00		UN45B_HUMAN (35-209): 6.51e-43: 171: 25.00
+	Hs
		468282 HS90B_HUMAN (1-724): 0: 1083: 100.00		FKBP4_HUMAN (2-211): 1.34e-43: 167: 18.98
+	Mm
		547256 HS90B_MOUSE (1-724): 0: 1086: 99.59		PPP5_MOUSE (15-262): 1.72e-42: 164: 14.94
+	Hs
		468210 HS90B_HUMAN (1-724): 0: 1083: 100.00		PPP5_HUMAN (15-262): 3.88e-43: 166: 15.71
+	Hs
		468915 HS90B_HUMAN (1-724): 0: 1083: 100.00		CHIP_HUMAN (12-294): 4.46e-43: 160: 16.88
+	Mm
		547287 HS90B_MOUSE (1-724): 0: 1086: 99.59		CHIP_MOUSE (10-294): 8.22e-42: 157: 15.82
+	Hs
		468336 HS90B_HUMAN (1-724): 0: 1083: 100.00		FKBP5_HUMAN (3-219): 7.91e-41: 159: 17.49
+	Hs
		117623 K9JA46_HUMAN (1-724): 0: 1069: 85.25		UN45B_HUMAN (35-209): 6.51e-43: 171: 25.00
+	Hs
		117619 K9JA46_HUMAN (1-724): 0: 1069: 85.25		FKBP4_HUMAN (2-211): 1.34e-43: 167: 18.98
+	Hs
		461376 HS90A_HUMAN (1-724): 0: 1069: 85.25		FKBP4_HUMAN (2-211): 1.34e-43: 167: 18.98
+	Hs
		117618 K9JA46_HUMAN (1-724): 0: 1069: 85.25		PPP5_HUMAN (15-262): 3.88e-43: 166: 15.71
+	Hs
		461300 HS90A_HUMAN (1-724): 0: 1069: 85.25		PPP5_HUMAN (15-262): 3.88e-43: 166: 15.71
+	Hs
		117620 K9JA46_HUMAN (1-724): 0: 1069: 85.25		FKBP5_HUMAN (3-219): 7.91e-41: 159: 17.49
+	Hs
		185366 HS90B_HUMAN (1-724): 0: 1083: 100.00		OGT1_HUMAN (3-314): 1.16e-23: 110: 9.09
+	Hs
		468302 HS90B_HUMAN (1-724): 0: 1083: 100.00		PPID_HUMAN (35-166): 1.19e-20: 96.9: 23.91
+	Hs
		468729 HS90B_HUMAN (1-724): 0: 1083: 100.00		DNJC7_HUMAN (10-171): 6.35e-20: 96.5: 24.70
+	Hs
		185361 HS90A_HUMAN (1-724): 0: 1069: 85.25		OGT1_HUMAN (3-314): 1.16e-23: 110: 9.09
+	Hs
		468409 HS90B_HUMAN (1-724): 0: 1083: 100.00		TOM34_HUMAN (36-168): 5.49e-19: 90.7: 28.47