HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: PSMD6 (Q15008)
26S proteasome non-ATPase regulatory subunit 6 (26S proteasome regulatory subunit RPN7) (26S proteasome regulatory subunit S10) (Breast cancer-associated protein SGA-113M) (Phosphonoformate immuno-associated protein 4) (Proteasome regulatory particle subunit p44S10) (p42A)
Gene: PSMD6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	28190767
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	RPN7~ubiquitin
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 389
+	Hs
		475555 UBC_HUMAN (1-685): 0: 846: 100.00		CSN2_HUMAN (22-388): 5.37e-90: 280: 13.67
+	Hs
		121666 UBC_HUMAN (1-685): 0: 846: 100.00		PSD11_HUMAN (3-387): 8.54e-77: 245: 11.03
+	Sc
		477452 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		RPN7_YEAST (11-389): 3.41e-86: 269: 35.47
+	At
		1091885 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		PSMD6_ARATH (12-389): 8.46e-116: 343: 53.95
+	At
		799469 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		CSN1_ARATH (17-389): 2.68e-95: 293: 19.47
+	Sc
		477496 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		RPN6_YEAST (30-389): 1.53e-56: 192: 12.57
+	Hs
		923997 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		PSMD6_HUMAN (1-389): 5.58e-137: 397: 100.00
+	Mm
		476962 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		PSMD6_MOUSE (1-389): 3.56e-136: 395: 97.94
+	Hs
		397972 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		PSMD6_HUMAN (1-389): 5.58e-137: 397: 100.00
+	At
		1092149 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		PSD11_ARATH (7-388): 4e-73: 235: 11.75
+	Mm
		102344 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		G3UXW9_MOUSE (12-389): 2.02e-98: 304: 21.48
+	Mm
		476740 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		CSN2_MOUSE (22-388): 5.37e-90: 280: 13.67
+	Rn
		897345 UBC_RAT (1-108): 1.27e-29: 127: 90.74		CSN2_RAT (22-388): 5.37e-90: 280: 13.67
+	Hs
		121730 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		PSD11_HUMAN (3-387): 8.54e-77: 245: 11.03
+	Mm
		476877 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		PSD11_MOUSE (3-387): 6.46e-77: 245: 11.03
+	Hs
		121663 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		PSD11_HUMAN (3-387): 8.54e-77: 245: 11.03