HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: UBP34 (Q70CQ2)
Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.4.19.12) (Deubiquitinating enzyme 34) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34)
Gene: USP34

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.806

Property	Details
Experiments	29576527, 35588869
Identification Methods	pull down, x-ray crystallography
Interaction Type	direct interaction, association

Property	Details
Interacting Pfam domains	UCH~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 685 Hs			1 3546
+	Hs
		476147 UBC_HUMAN (1-685): 0: 846: 100.00		UBP7_HUMAN (1840-2471): 3.16e-125: 428: 18.08
+	Hs
		476213 UBC_HUMAN (1-685): 0: 846: 100.00		UBP47_HUMAN (1737-2299): 8.3e-110: 387: 19.22
+	Hs
		476452 UBC_HUMAN (1-685): 0: 846: 100.00		UBP40_HUMAN (1882-2459): 8.19e-99: 352: 18.15
+	Hs
		476493 UBC_HUMAN (1-685): 0: 846: 100.00		UBP36_HUMAN (1761-2263): 3.87e-97: 344: 18.32
+	Hs
		475995 UBC_HUMAN (1-685): 0: 846: 100.00		UBP48_HUMAN (1828-2270): 1.54e-95: 337: 24.20
+	Hs
		476579 UBC_HUMAN (1-685): 0: 846: 100.00		UBP22_HUMAN (1868-2239): 3.06e-100: 336: 18.23
+	Hs
		64200 UBC_HUMAN (1-685): 0: 846: 100.00		UBP27_HUMAN (1868-2255): 7.89e-98: 325: 17.36
+	Hs
		476146 UBC_HUMAN (1-685): 0: 846: 100.00		USP9X_HUMAN (208-450): 1.05e-86: 320: 25.10
+	Hs
		131635 UBC_HUMAN (1-685): 0: 846: 100.00		USP9Y_HUMAN (208-450): 3.74e-86: 319: 24.71
+	Hs
		475932 UBC_HUMAN (1-685): 0: 846: 100.00		U17L2_HUMAN (1825-2270): 5.76e-94: 318: 16.34
+	Hs
		259261 UBC_HUMAN (1-685): 0: 846: 100.00		UBP12_HUMAN (1893-2240): 9.21e-96: 317: 22.61
+	Hs
		475566 UBC_HUMAN (1-685): 0: 846: 100.00		UBP46_HUMAN (1893-2240): 9.44e-96: 317: 23.14
+	Hs
		476580 UBC_HUMAN (1-685): 0: 846: 100.00		UBP24_HUMAN (208-450): 1.6e-64: 248: 14.40
+	At
		1091741 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		UBP13_ARATH (1721-2469): 3.29e-147: 493: 19.72
+	At
		1092066 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		UBP12_ARATH (1678-2469): 4.43e-146: 490: 18.59
+	Sc
		477365 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		UBP15_YEAST (1879-2361): 4.86e-109: 382: 20.84
+	Dm
		1099208 R9PY16_DROME (457-685): 5.07e-80: 258: 90.39		UBPE_DROME (1731-2528): 1.47e-137: 475: 17.89
+	Mm
		476669 UBB_MOUSE (457-685): 2.3e-86: 275: 99.56		UBP48_MOUSE (1828-2270): 8.89e-94: 333: 24.42
+	Hs
		924201 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		UBP36_HUMAN (1761-2263): 3.87e-97: 344: 18.32
+	Hs
		924100 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		USP9X_HUMAN (208-450): 1.05e-86: 320: 25.10