HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: UBP45 (Q70EL2)
Ubiquitin carboxyl-terminal hydrolase 45 (EC 3.4.19.12) (Deubiquitinating enzyme 45) (Ubiquitin thioesterase 45) (Ubiquitin-specific-processing protease 45)
Gene: USP45

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	29576527
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UCH~ubiquitin, ubiquitin~zf-UBP
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 685 Hs			1 814
+	Hs
		476644 UBC_HUMAN (1-685): 0: 846: 100.00		UBP16_HUMAN (15-814): 1.68e-166: 504: 35.97
+	Hs
		476097 UBC_HUMAN (1-685): 0: 846: 100.00		UBP33_HUMAN (8-812): 9.02e-121: 388: 18.62
+	Hs
		475502 UBC_HUMAN (1-685): 0: 846: 100.00		UBP11_HUMAN (172-812): 6.85e-118: 381: 16.74
+	Hs
		475693 UBC_HUMAN (1-685): 0: 846: 100.00		UBP4_HUMAN (173-812): 8.89e-118: 381: 17.07
+	Hs
		476599 UBC_HUMAN (1-685): 0: 846: 100.00		UBP20_HUMAN (35-812): 1.97e-116: 376: 18.44
+	Hs
		476624 UBC_HUMAN (1-685): 0: 846: 100.00		UBP15_HUMAN (170-812): 2.88e-109: 359: 17.49
+	Hs
		476067 UBC_HUMAN (1-685): 0: 846: 100.00		UBP32_HUMAN (78-729): 2.39e-94: 325: 15.10
+	Hs
		475954 UBC_HUMAN (1-685): 0: 846: 100.00		UBP31_HUMAN (189-812): 1.02e-93: 322: 18.79
+	Hs
		475403 UBC_HUMAN (1-685): 0: 846: 100.00		UBP6_HUMAN (154-729): 2.14e-82: 290: 14.84
+	Hs
		476145 UBC_HUMAN (1-685): 0: 846: 100.00		UBP13_HUMAN (28-813): 6.12e-75: 263: 12.58
+	Hs
		296262 UBC_HUMAN (1-685): 0: 846: 100.00		UBP1_HUMAN (134-793): 8.29e-72: 253: 18.04
+	Hs
		475461 UBC_HUMAN (1-685): 0: 846: 100.00		UBP5_HUMAN (14-552): 2.13e-71: 253: 12.65
+	Hs
		301354 UBC_HUMAN (1-685): 0: 846: 100.00		UBP19_HUMAN (216-812): 8.52e-52: 198: 15.01
+	Hs
		476579 UBC_HUMAN (1-685): 0: 846: 100.00		UBP22_HUMAN (444-814): 1.04e-49: 185: 16.01
+	Hs
		271022 UBC_HUMAN (1-685): 0: 846: 100.00		UBP2_HUMAN (588-811): 1.06e-45: 175: 25.22
+	Hs
		476658 UBC_HUMAN (1-685): 0: 846: 100.00		UBP3_HUMAN (469-810): 8.99e-42: 162: 18.61
+	Hs
		64200 UBC_HUMAN (1-685): 0: 846: 100.00		UBP27_HUMAN (619-812): 3.24e-14: 77.8: 25.49
+	Dm
		477538 UBIQP_DROME (1-610): 0: 752: 99.84		NOT_DROME (541-812): 3.8e-40: 157: 19.12
+	At
		1210479 UBQ10_ARATH (305-685): 2.63e-153: 453: 95.80		UBP15_ARATH (619-812): 6.85e-13: 74.7: 29.80
+	Sc
		477366 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		UBP8_YEAST (668-810): 6.65e-15: 80.1: 34.90