HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: R144B (Q7Z419)
E3 ubiquitin-protein ligase RNF144B (EC 2.3.2.31) (IBR domain-containing protein 2) (RING finger protein 144B) (p53-inducible RING finger protein)
Gene: RNF144B

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	28943312
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	IBR~ubiquitin
Common GO terms	GO:0005829 - cytosol
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 303
+	Hs
		475939 UBC_HUMAN (1-685): 0: 846: 100.00		RN19B_HUMAN (15-284): 3.13e-79: 256: 24.56
+	Hs
		475494 UBC_HUMAN (1-685): 0: 846: 100.00		R144A_HUMAN (13-293): 3.76e-77: 238: 54.42
+	Hs
		476630 UBC_HUMAN (1-685): 0: 846: 100.00		ARI1_HUMAN (22-242): 6.38e-67: 220: 26.79
+	Hs
		312458 UBC_HUMAN (1-685): 0: 846: 100.00		ARI2_HUMAN (8-250): 3.66e-67: 219: 25.61
+	Hs
		476496 UBC_HUMAN (1-685): 0: 846: 100.00		AKIB1_HUMAN (30-240): 1.2e-61: 213: 21.01
+	Hs
		476187 UBC_HUMAN (1-685): 0: 846: 100.00		RNF31_HUMAN (8-237): 4.55e-47: 171: 19.92
+	Dm
		477528 UBIQP_DROME (1-610): 0: 752: 99.84		LUBEL_DROME (12-258): 3.97e-54: 191: 17.54
+	Dm
		1214032 Q9W418_DROME (229-685): 0: 557: 99.78		LUBEL_DROME (12-258): 3.97e-54: 191: 17.54
+	Sc
		477225 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		HEL1_YEAST (20-249): 2.01e-57: 194: 21.85
+	At
		1092233 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		Q9M1E9_ARATH (10-236): 2.51e-47: 165: 23.50
+	Hs
		475069 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		RN19B_HUMAN (15-284): 3.13e-79: 256: 24.56
+	Hs
		475094 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		CUL9_HUMAN (3-239): 8.25e-66: 225: 22.36
+	Hs
		312457 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		ARI2_HUMAN (8-250): 3.66e-67: 219: 25.61
+	Hs
		475133 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		RNF31_HUMAN (8-237): 4.55e-47: 171: 19.92
+	Mm
		476959 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		RNF31_MOUSE (30-222): 5.17e-11: 65.5: 24.40