Interactor 1: ACM5 (P08912)
Muscarinic acetylcholine receptor M5
Gene: CHRM5
Interactor 2: ACM3 (P20309)
Muscarinic acetylcholine receptor M3
Gene: CHRM3
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.44 | 1.00 | 0.665 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 20398705 |
| Identification Methods | anti bait coimmunoprecipitation, anti tag coimmunoprecipitation |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | 7tm_1~7tm_1 |
| Common GO terms | GO:0004435 - phosphatidylinositol-4,5-bisphosphate phospholipase C activity GO:0005886 - plasma membrane GO:0007187 - G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger GO:0007197 - adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway GO:0007213 - G protein-coupled acetylcholine receptor signaling pathway and 5 others more... |
| Homologous interactions | 17 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025