HitPredict

Interactor 1: LEG1 (P09382)
Galectin-1 (Gal-1) (14 kDa laminin-binding protein) (HLBP14) (14 kDa lectin) (Beta-galactoside-binding lectin L-14-I) (Galaptin) (HBL) (HPL) (Lactose-binding lectin 1) (Lectin galactoside-binding soluble 1) (Putative MAPK-activating protein PM12) (S-Lac lectin 1)
Gene: LGALS1

Interactor 2: LRP1 (Q07954)
Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)]
Gene: LRP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 135 Hs			1 4544
+	Hs
		125424 LEG9_HUMAN (10-133): 1.51e-35: 126: 31.50		LRP1_HUMAN (24-4544): 0: 3504: 100.00
+	Hs
		480790 LEG1_HUMAN (1-135): 1.21e-53: 166: 100.00		NID2_HUMAN (1679-1844): 1.09e-11: 74.1: 24.86
+	Hs
		480767 LEG1_HUMAN (1-135): 1.21e-53: 166: 100.00		LRP2_HUMAN (2-286): 2.25e-10: 69.9: 13.86
+	Hs
		480869 LEG1_HUMAN (1-135): 1.21e-53: 166: 100.00		SORL_HUMAN (1080-1344): 6.87e-10: 68.3: 13.65
+	Hs
		376465 LEG1_HUMAN (1-135): 1.21e-53: 166: 100.00		LDLR_HUMAN (4098-4307): 8.05e-10: 67.6: 13.72
+	Hs
		609676 LEG3_HUMAN (3-134): 1.12e-48: 158: 28.47		NID2_HUMAN (1679-1844): 1.09e-11: 74.1: 24.86
+	Hs
		480677 LEG1_HUMAN (1-135): 1.21e-53: 166: 100.00		NID1_HUMAN (3259-3502): 3.72e-09: 65.6: 13.18
+	Hs
		287514 LEG1_HUMAN (1-135): 1.21e-53: 166: 100.00		LRP6_HUMAN (1068-1243): 9.55e-09: 64.5: 21.62
+	Hs
		572678 LEG3_HUMAN (3-134): 1.12e-48: 158: 28.47		NID1_HUMAN (3259-3502): 3.72e-09: 65.6: 13.18
+	Hs
		868688 LEG7_HUMAN (1-132): 4.87e-45: 145: 33.58		NID2_HUMAN (1679-1844): 1.09e-11: 74.1: 24.86
+	Hs
		125448 LEG9_HUMAN (10-133): 1.51e-35: 126: 31.50		NID2_HUMAN (1679-1844): 1.09e-11: 74.1: 24.86
+	Hs
		127382 LEG8_HUMAN (12-134): 1.8e-36: 128: 28.13		SORL_HUMAN (1080-1344): 6.87e-10: 68.3: 13.65
+	Hs
		125551 LEG9_HUMAN (10-133): 1.51e-35: 126: 31.50		SORL_HUMAN (1080-1344): 6.87e-10: 68.3: 13.65
+	Hs
		125198 LEG9_HUMAN (10-133): 1.51e-35: 126: 31.50		NID1_HUMAN (3259-3502): 3.72e-09: 65.6: 13.18