HitPredict

Interactor 1: ANDR (P10275)
Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)
Gene: AR

Interactor 2: MCM2 (P49736)
DNA replication licensing factor MCM2 (EC 3.6.4.12) (Minichromosome maintenance protein 2 homolog) (Nuclear protein BM28)
Gene: MCM2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	32814769
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0019899 - enzyme binding
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 920 Hs			1 904
+	Hs
		487175 ANDR_HUMAN (1-920): 0: 966: 100.00		MCM5_HUMAN (169-902): 0: 768: 29.43
+	Hs
		487140 ANDR_HUMAN (1-920): 0: 966: 100.00		MCM3_HUMAN (186-897): 0: 725: 29.20
+	Hs
		487176 ANDR_HUMAN (1-920): 0: 966: 100.00		MCM7_HUMAN (188-886): 0: 707: 27.35
+	Hs
		369192 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		MCM2_HUMAN (1-904): 0: 1078: 100.00
+	Hs
		832615 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		MCM2_HUMAN (1-904): 0: 1078: 100.00
+	Hs
		369080 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		MCM4_HUMAN (2-885): 0: 847: 28.42
+	Hs
		369081 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		MCM5_HUMAN (169-902): 0: 768: 29.43
+	Hs
		377136 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		MCM5_HUMAN (169-902): 0: 768: 29.43
+	Hs
		369009 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		MCM3_HUMAN (186-897): 0: 725: 29.20
+	Hs
		708712 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		MCM5_HUMAN (169-902): 0: 768: 29.43
+	Hs
		369082 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		MCM7_HUMAN (188-886): 0: 707: 27.35
+	Hs
		627317 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		MCM3_HUMAN (186-897): 0: 725: 29.20