HitPredict

Interactor 1: ANDR (P10275)
Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)
Gene: AR

Interactor 2: NCOA1 (Q15788)
Nuclear receptor coactivator 1 (NCoA-1) (EC 2.3.1.48) (Class E basic helix-loop-helix protein 74) (bHLHe74) (Protein Hin-2) (RIP160) (Renal carcinoma antigen NY-REN-52) (Steroid receptor coactivator 1) (SRC-1)
Gene: NCOA1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.965

The method score is based on:

Property Details
Experiments 10567563, 10731636, 15256534, 33640491, 35785414, 12163482, 17353003, 23975195
Identification Methods pull down, two hybrid, proximity labelling technology, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Hormone_recep~SRC-1
Common GO terms GO:0000785 - chromatin
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
and 5 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

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Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024