HitPredict

Interactor 1: IFIT2 (P09913)
Interferon-induced protein with tetratricopeptide repeats 2 (IFIT-2) (ISG-54 K) (Interferon-induced 54 kDa protein) (IFI-54K) (P54)
Gene: IFIT2

Interactor 2: IFIT1 (P09914)
Antiviral innate immune response effector IFIT1 (IFIT-1) (Interferon-induced 56 kDa protein) (IFI-56K) (P56) (Interferon-induced protein with tetratricopeptide repeats 1)
Gene: IFIT1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.83 1.00 0.916

The method score is based on:

Property Details
Experiments 28514442, 33961781, 38334954, 21642987
Identification Methods affinity chromatography technology, cross-linking study, pull down, anti tag coimmunoprecipitation, molecular sieving
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains TPR_12~TPR_8, TPR_2~TPR_8, TPR_8~TPR_8
Common GO terms GO:0003723 - RNA binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0009615 - response to virus
GO:0032091 - negative regulation of protein binding
and 2 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 472
Hs

1 478
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Last updated: 11Aug2025