HitPredict

Interactor 1: CDC27 (P30260)
Cell division cycle protein 27 homolog (Anaphase-promoting complex subunit 3) (APC3) (CDC27 homolog) (CDC27Hs) (H-NUC)
Gene: CDC27

Interactor 2: CDC27 (P30260)
Cell division cycle protein 27 homolog (Anaphase-promoting complex subunit 3) (APC3) (CDC27 homolog) (CDC27Hs) (H-NUC)
Gene: CDC27

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 1.00 0.951

The method score is based on:

Property Details
Experiments 25490258, 32152539, 35440621, 31839598, 21335556, 16648845, 22100920
Identification Methods x-ray crystallography, affinity chromatography technology, pull down, cross-linking study
Interaction Type association, physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains ANAPC3~ANAPC3, ANAPC3~TPR_8, TPR_1~TPR_1, TPR_1~TPR_8, TPR_8~TPR_8
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005680 - anaphase-promoting complex
GO:0005737 - cytoplasm
GO:0005813 - centrosome
and 14 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 824
Hs

1 824
+ Hs
+ Mm
+ Hs
+ Hs
+ Xl
+ Xl
+ Xl
+ Xl
+ Dm
+ Hs
+ Sp
+ Sp
+ Hs
+ Hs
+ Sp
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025