Interactor 1: FBSP1 (P0C2W1)
F-box/SPRY domain-containing protein 1 (F-box only protein 45) (hFbxo45)
Gene: FBXO45

Interactor 2: FBXW7 (Q969H0)
F-box/WD repeat-containing protein 7 (Archipelago homolog) (hAgo) (F-box and WD-40 domain-containing protein 7) (F-box protein FBX30) (SEL-10) (hCdc4)
Gene: FBXW7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 1.00 0.929

The method score is based on:

Property Details
Experiments 31285543, 25720964, 28514442, 33961781, unassigned3799
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains F-box-like~F-box-like
Common GO terms GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006974 - DNA damage response
GO:0016567 - protein ubiquitination
and 3 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 286
Hs

1 707
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Service provided by Combinatics, Japan

Last updated: 11Aug2025