HitPredict

Interactor 1: LAMP1 (P11279)
Lysosome-associated membrane glycoprotein 1 (LAMP-1) (Lysosome-associated membrane protein 1) (CD107 antigen-like family member A) (CD antigen CD107a)
Gene: LAMP1

Interactor 2: VAMP2 (P63027)
Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin-2)
Gene: VAMP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	29568061, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0008021 - synaptic vesicle GO:0016020 - membrane GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 417 Hs			1 116
+	Hs
		506936 LAMP1_HUMAN (1-417): 6.95e-180: 509: 100.00		VAMP7_HUMAN (3-96): 2.69e-30: 109: 31.31
+	Hs
		261630 LAMP1_HUMAN (1-417): 6.95e-180: 509: 100.00		VAMP4_HUMAN (18-99): 1.04e-26: 97.8: 35.37
+	Hs
		263149 LAMP1_HUMAN (1-417): 6.95e-180: 509: 100.00		SC22B_HUMAN (1-115): 4.12e-24: 93.2: 17.09
+	Hs
		180798 LAMP1_HUMAN (1-417): 6.95e-180: 509: 100.00		YKT6_HUMAN (5-85): 5.79e-24: 92.4: 24.69
+	Hs
		507033 LAMP1_HUMAN (1-417): 6.95e-180: 509: 100.00		VAMP3_HUMAN (26-98): 7.88e-25: 92: 91.78
+	Hs
		507213 LAMP1_HUMAN (1-417): 6.95e-180: 509: 100.00		VAMP8_HUMAN (20-99): 2.06e-24: 90.9: 32.50
+	Hs
		527361 LAMP2_HUMAN (4-415): 3.06e-170: 484: 34.94		VAMP7_HUMAN (3-96): 2.69e-30: 109: 31.31
+	Hs
		261632 LAMP2_HUMAN (4-415): 3.06e-170: 484: 34.94		VAMP4_HUMAN (18-99): 1.04e-26: 97.8: 35.37
+	Hs
		527385 LAMP2_HUMAN (4-415): 3.06e-170: 484: 34.94		VAMP2_HUMAN (25-116): 9.9e-26: 94.7: 100.00
+	Hs
		263154 LAMP2_HUMAN (4-415): 3.06e-170: 484: 34.94		SC22B_HUMAN (1-115): 4.12e-24: 93.2: 17.09
+	Hs
		180803 LAMP2_HUMAN (4-415): 3.06e-170: 484: 34.94		YKT6_HUMAN (5-85): 5.79e-24: 92.4: 24.69
+	Hs
		527468 LAMP2_HUMAN (4-415): 3.06e-170: 484: 34.94		VAMP3_HUMAN (26-98): 7.88e-25: 92: 91.78
+	Hs
		527764 LAMP2_HUMAN (4-415): 3.06e-170: 484: 34.94		VAMP8_HUMAN (20-99): 2.06e-24: 90.9: 32.50
+	Hs
		850608 LAMP3_HUMAN (157-417): 2.56e-77: 247: 26.05		VAMP7_HUMAN (3-96): 2.69e-30: 109: 31.31
+	Hs
		261741 LAMP3_HUMAN (157-417): 2.56e-77: 247: 26.05		VAMP4_HUMAN (18-99): 1.04e-26: 97.8: 35.37
+	Hs
		926268 LAMP3_HUMAN (157-417): 2.56e-77: 247: 26.05		VAMP2_HUMAN (25-116): 9.9e-26: 94.7: 100.00
+	Hs
		263393 LAMP3_HUMAN (157-417): 2.56e-77: 247: 26.05		SC22B_HUMAN (1-115): 4.12e-24: 93.2: 17.09
+	Hs
		180957 LAMP3_HUMAN (157-417): 2.56e-77: 247: 26.05		YKT6_HUMAN (5-85): 5.79e-24: 92.4: 24.69
+	Hs
		1079470 LAMP3_HUMAN (157-417): 2.56e-77: 247: 26.05		VAMP3_HUMAN (26-98): 7.88e-25: 92: 91.78
+	Hs
		1313467 LAMP3_HUMAN (157-417): 2.56e-77: 247: 26.05		VAMP8_HUMAN (20-99): 2.06e-24: 90.9: 32.50