HitPredict

Interactor 1: Q1KLZ0 (Q1KLZ0)
HCG15971, isoform CRA_a (PS1TP5-binding protein 1)
Gene: PS1TP5BP1

Interactor 2: Q549N0 (Q549N0)
Cofilin 2 (Muscle), isoform CRA_a (Cofilin 2 (Muscle), isoform CRA_c) (Cofilin isoform) (cDNA, FLJ94864, Homo sapiens cofilin 2 (muscle) (CFL2), mRNA)
Gene: CFL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.80	0.594

Property	Details
Experiments	25416956
Identification Methods	two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Actin~Cofilin_ADF
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 375 Hs			1 166
+	Hs
		660089 ACTBL_HUMAN (2-375): 0: 735: 91.71		COF1_HUMAN (1-166): 3.76e-73: 218: 80.72
+	Hs
		1200975 ACTBL_HUMAN (2-375): 0: 735: 91.71		TWF2_HUMAN (3-151): 2.44e-29: 111: 18.42
+	Hs
		506961 POTEI_HUMAN (1-375): 0: 731: 91.20		TWF2_HUMAN (3-151): 2.44e-29: 111: 18.42
+	Mm
		616470 ACTB_MOUSE (1-375): 0: 603: 100.00		COF1_MOUSE (1-166): 1.73e-73: 219: 80.72
+	Hs
		952874 ACTB_HUMAN (1-375): 0: 603: 100.00		Q549N0_HUMAN (1-166): 1.39e-73: 219: 100.00
+	Hs
		953195 ACTB_HUMAN (1-375): 0: 603: 100.00		COF2_HUMAN (1-166): 1.39e-73: 219: 100.00
+	Hs
		660017 ACTB_HUMAN (1-375): 0: 603: 100.00		COF1_HUMAN (1-166): 3.76e-73: 218: 80.72
+	Hs
		660081 Q1KLZ0_HUMAN (1-375): 0: 603: 100.00		COF1_HUMAN (1-166): 3.76e-73: 218: 80.72
+	Rn
		852477 ACTB_RAT (1-375): 0: 603: 100.00		COF1_RAT (1-166): 3.37e-73: 218: 81.33
+	Hs
		993207 ACTG_HUMAN (1-375): 0: 601: 98.93		Q549N0_HUMAN (1-166): 1.39e-73: 219: 100.00
+	Hs
		660028 ACTG_HUMAN (1-375): 0: 601: 98.93		COF1_HUMAN (1-166): 3.76e-73: 218: 80.72
+	Hs
		952697 ACTB_HUMAN (1-375): 0: 603: 100.00		DEST_HUMAN (1-166): 2.98e-69: 208: 68.68
+	Hs
		955834 Q1KLZ0_HUMAN (1-375): 0: 603: 100.00		DEST_HUMAN (1-166): 2.98e-69: 208: 68.68
+	Hs
		955818 ACTG_HUMAN (1-375): 0: 601: 98.93		DEST_HUMAN (1-166): 2.98e-69: 208: 68.68
+	Hs
		952782 ACTB_HUMAN (1-375): 0: 603: 100.00		TWF1_HUMAN (3-156): 3.6e-33: 121: 21.66
+	Hs
		993148 ACTG_HUMAN (1-375): 0: 601: 98.93		TWF1_HUMAN (3-156): 3.6e-33: 121: 21.66
+	Hs
		952698 ACTB_HUMAN (1-375): 0: 603: 100.00		GMFB_HUMAN (1-154): 2.31e-33: 116: 19.11
+	Hs
		955875 ACTG_HUMAN (1-375): 0: 601: 98.93		GMFB_HUMAN (1-154): 2.31e-33: 116: 19.11
+	Hs
		952893 ACTB_HUMAN (1-375): 0: 603: 100.00		TWF2_HUMAN (3-151): 2.44e-29: 111: 18.42
+	Hs
		993215 ACTG_HUMAN (1-375): 0: 601: 98.93		TWF2_HUMAN (3-151): 2.44e-29: 111: 18.42