HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: UBE2H (P62256)
Ubiquitin-conjugating enzyme E2 H (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme H) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme H) (UbcH2) (Ubiquitin carrier protein H) (Ubiquitin-conjugating enzyme E2-20K) (Ubiquitin-protein ligase H)
Gene: UBE2H

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	27182664
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UQ_con~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 685 Hs			1 183
+	Hs
		508868 UBC_HUMAN (1-685): 0: 857: 100.00		UB2D4_HUMAN (7-150): 4.74e-73: 218: 31.08
+	Hs
		507793 UBC_HUMAN (1-685): 0: 857: 100.00		UB2D2_HUMAN (7-150): 1.43e-72: 217: 29.73
+	Hs
		507701 UBC_HUMAN (1-685): 0: 857: 100.00		UB2D1_HUMAN (7-150): 3.92e-72: 215: 32.43
+	Hs
		507755 UBC_HUMAN (1-685): 0: 857: 100.00		UB2D3_HUMAN (7-150): 7.96e-71: 212: 29.05
+	Hs
		508388 UBC_HUMAN (1-685): 0: 857: 100.00		UB2E3_HUMAN (5-150): 6.66e-65: 199: 28.00
+	Hs
		508456 UBC_HUMAN (1-685): 0: 857: 100.00		UB2E2_HUMAN (5-150): 6.07e-65: 199: 27.33
+	Hs
		507680 UBC_HUMAN (1-685): 0: 857: 100.00		UBE2A_HUMAN (4-150): 3.11e-64: 196: 30.46
+	Hs
		507705 UBC_HUMAN (1-685): 0: 857: 100.00		UB2E1_HUMAN (5-150): 7.21e-64: 196: 27.33
+	Hs
		507805 UBC_HUMAN (1-685): 0: 857: 100.00		UBE2B_HUMAN (4-149): 3.16e-63: 193: 30.67
+	Rn
		92896 UBC_RAT (1-637): 0: 779: 98.90		UB2D1_RAT (7-150): 3.92e-72: 215: 32.43
+	Xl
		982387 Q7SY79_XENLA (77-685): 0: 752: 99.84		UB2D2_XENLA (7-150): 1.43e-72: 217: 29.73
+	Dm
		683066 Q9W418_DROME (229-685): 0: 567: 99.78		UBCD1_DROME (7-150): 5.69e-72: 215: 29.73
+	Sc
		509374 UBI4P_YEAST (381-685): 4.09e-126: 380: 95.74		UBC4_YEAST (1-149): 1.6e-70: 212: 32.03
+	At
		762746 UBQ3_ARATH (457-685): 4e-89: 282: 95.63		UBC8_ARATH (7-151): 6.78e-72: 215: 30.20
+	At
		762762 UBQ3_ARATH (457-685): 4e-89: 282: 95.63		UBC9_ARATH (7-151): 2.12e-71: 214: 30.20
+	At
		762777 UBQ3_ARATH (457-685): 4e-89: 282: 95.63		UBC10_ARATH (7-151): 2.88e-71: 213: 30.20
+	At
		762787 UBQ3_ARATH (457-685): 4e-89: 282: 95.63		UBC11_ARATH (7-151): 2.58e-71: 213: 29.53
+	At
		683037 UBQ3_ARATH (457-685): 4e-89: 282: 95.63		UBC1_ARATH (4-152): 2.39e-64: 196: 29.41
+	Sc
		509394 UBI4P_YEAST (381-685): 4.09e-126: 380: 95.74		UBC1_YEAST (38-153): 1.18e-22: 92: 37.93
+	Sc
		509643 UBI4P_YEAST (381-685): 4.09e-126: 380: 95.74		UBC13_YEAST (31-152): 1.48e-22: 90.1: 37.71