HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: MARH2 (Q9P0N8)
E3 ubiquitin-protein ligase MARCHF2 (EC 2.3.2.27) (Membrane-associated RING finger protein 2) (Membrane-associated RING-CH protein II) (MARCH-II) (RING finger protein 172) (RING-type E3 ubiquitin transferase MARCHF2)
Gene: MARCHF2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	14722266
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005789 - endoplasmic reticulum membrane GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0010008 - endosome membrane and 1 others more... GO:0016567 - protein ubiquitination
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 246
+	Hs
		508319 UBC_HUMAN (1-685): 0: 857: 100.00		MARH1_HUMAN (5-230): 4.19e-67: 210: 23.08
+	Hs
		508103 UBC_HUMAN (1-685): 0: 857: 100.00		MARH8_HUMAN (51-239): 4.52e-59: 190: 26.53
+	Rn
		1205348 UBC_RAT (1-637): 0: 779: 98.90		MARH2_RAT (1-246): 3.39e-89: 265: 95.53
+	Hs
		508754 UBC_HUMAN (1-685): 0: 857: 100.00		MARH4_HUMAN (50-230): 1.02e-50: 172: 20.88
+	Hs
		246272 UBC_HUMAN (1-685): 0: 857: 100.00		MARH6_HUMAN (57-245): 9.67e-47: 167: 21.15
+	Rn
		1220215 UBC_RAT (1-637): 0: 779: 98.90		MARH3_RAT (1-246): 8.68e-78: 236: 64.43
+	Hs
		508724 UBC_HUMAN (1-685): 0: 857: 100.00		MARH5_HUMAN (64-235): 2.78e-33: 123: 17.71
+	Hs
		508649 UBC_HUMAN (1-685): 0: 857: 100.00		MARH7_HUMAN (64-115): 3.31e-14: 73.3: 33.87
+	Sc
		509583 UBI4P_YEAST (381-685): 4.09e-126: 380: 95.74		DOA10_YEAST (56-221): 2.21e-33: 129: 18.18