Protein: MARH7
E3 ubiquitin-protein ligase MARCHF7 (EC 2.3.2.27) (Axotrophin) (Membrane-associated RING finger protein 7) (Membrane-associated RING-CH protein VII) (MARCH-VII) (RING finger protein 177) (RING-type E3 ubiquitin transferase MARCHF7)

Gene: MARH7, MARCHF7
Organism: Homo sapiens
Interactions: 89
UniProt ID: Q9H992

Gene Ontology (top 5):
GO:0002643 - regulation of tolerance induction
GO:0005634 - nucleus
GO:0005813 - centrosome
GO:0005829 - cytosol
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

957672

UBE2K
Ubiquitin-conjugating enzyme E2 K

6

19

Small-scale

0.728

High

789017

TGFR2
TGF-beta receptor type-2

5

6

Small-scale

0.712

High

957844

UBE2N
Ubiquitin-conjugating enzyme E2 N

4

15

Small-scale

0.696

High

1371695

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

4

3

Small-scale

0.682

High

1152249

MARE1
Microtubule-associated protein RP/EB family member 1

3

1

High-throughput

0.665

High

922779

CCHL
Holocytochrome c-type synthase

3

0

High-throughput

0.638

High

1046422

UBXN1
UBX domain-containing protein 1

3

0

High-throughput

0.638

High

1399391

NLRP3
NACHT, LRR and PYD domains-containing protein 3

2

2

Small-scale

0.634

High

909391

UB2E1
Ubiquitin-conjugating enzyme E2 E1

2

16

Small-scale

0.602

High

1311524

BBS7
BBSome complex member BBS7

2

0

High-throughput

0.602

High

913679

VAV2
Guanine nucleotide exchange factor VAV2

2

1

Small-scale

0.600

High

906785

UB2D1
Ubiquitin-conjugating enzyme E2 D1

2

16

Small-scale

0.594

High

1371538

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

2

3

Small-scale

0.584

High

269380

HSF2B
Heat shock factor 2-binding protein

2

0

High-throughput

0.580

High

1315133

EXOC8
Exocyst complex component 8

2

0

High-throughput

0.580

High

1436866

KCNE3
Potassium voltage-gated channel subfamily E member 3

2

0

High-throughput

0.576

High

530386

TAU
Microtubule-associated protein tau

1

1

Small-scale

0.573

High

1252975

BAKOR
Beclin 1-associated autophagy-related key regulator

1

0

High-throughput

0.554

High

1436863

MARE3
Microtubule-associated protein RP/EB family member 3

2

1

High-throughput

0.553

High

1252779

RN111
E3 ubiquitin-protein ligase Arkadia

1

2

High-throughput

0.541

High

1028398

MDM2
E3 ubiquitin-protein ligase Mdm2

1

0

Small-scale

0.537

High

1140148

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

0

Small-scale

0.537

High

347337

BAG2
BAG family molecular chaperone regulator 2

1

1

High-throughput

0.536

High

848078

AL3B1
Aldehyde dehydrogenase family 3 member B1

1

2

High-throughput

0.536

High

1116842

AVR2B
Activin receptor type-2B

1

6

High-throughput

0.536

High

1315854

AN13A
Ankyrin repeat domain-containing protein 13A

1

3

High-throughput

0.536

High

1325792

FXL16
F-box/LRR-repeat protein 16

1

1

High-throughput

0.536

High

1406991

NPAS1
Neuronal PAS domain-containing protein 1

1

1

High-throughput

0.536

High

1413493

AASD1
Alanyl-tRNA editing protein Aarsd1

1

1

High-throughput

0.536

High

1415594

AFG2B
ATPase family gene 2 protein homolog B

1

1

High-throughput

0.536

High

1436865

ASB4
Ankyrin repeat and SOCS box protein 4

1

2

High-throughput

0.536

High

957202

UB2D3
Ubiquitin-conjugating enzyme E2 D3

1

16

Small-scale

0.527

High

1245066

TRI65
E3 ubiquitin-protein ligase TRIM65

1

0

High-throughput

0.518

High

48174

IFT56
Intraflagellar transport protein 56

1

0

High-throughput

0.513

High

66459

ASB14
Ankyrin repeat and SOCS box protein 14

1

0

High-throughput

0.513

High

298229

DCTN3
Dynactin subunit 3

1

0

High-throughput

0.513

High

317372

ACL6B
Actin-like protein 6B

1

0

High-throughput

0.513

High

366440

FA12
Coagulation factor XII

1

0

High-throughput

0.513

High

457707

TBB5
Tubulin beta chain

1

0

High-throughput

0.513

High

679400

DNJB2
DnaJ homolog subfamily B member 2

1

0

High-throughput

0.513

High

1064598

HDHD1
Pseudouridine-5'-phosphatase

1

0

High-throughput

0.513

High

1161219

MK06
Mitogen-activated protein kinase 6

1

0

High-throughput

0.513

High

1163941

UPP1
Uridine phosphorylase 1

1

0

High-throughput

0.513

High

1178890

CF184
Cilia- and flagella-associated protein 184

1

0

High-throughput

0.513

High

1207266

SOLH1
Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1

1

0

High-throughput

0.513

High

1233800

CNDH2
Condensin-2 complex subunit H2

1

0

High-throughput

0.513

High

1382534

TRI52
E3 ubiquitin-protein ligase TRIM52

1

0

High-throughput

0.513

High

1436860

AAKG3
5'-AMP-activated protein kinase subunit gamma-3

1

0

High-throughput

0.513

High

508649

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

7

Small-scale

0.501

High

982324

UB2D2
Ubiquitin-conjugating enzyme E2 D2

1

16

Small-scale

0.501

High

1436859

MARH7
E3 ubiquitin-protein ligase MARCHF7

1

5

Small-scale

0.501

High

1429452

DRC3
Dynein regulatory complex subunit 3

1

3

High-throughput

0.489

High

593873

PP2BB
Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform

1

2

Small-scale

0.481

High

957518

UBC12
NEDD8-conjugating enzyme Ubc12

1

16

Small-scale

0.481

High

1062404

PP2BA
Protein phosphatase 3 catalytic subunit alpha

1

2

Small-scale

0.481

High

173381

XPO1
Exportin-1

1

1

High-throughput

0.479

High

1161402

HIF1A
Hypoxia-inducible factor 1-alpha

1

1

Small-scale

0.479

High

1270286

BT2A1
Butyrophilin subfamily 2 member A1

1

1

High-throughput

0.479

High

1436862

XPO7
Exportin-7

1

1

High-throughput

0.479

High

831448

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

1045779

TF65
Transcription factor p65

1

0

High-throughput

0.458

High

1178383

CL16A
Protein CLEC16A

1

0

High-throughput

0.458

High

1204659

TFDP3
Transcription factor Dp family member 3

1

0

High-throughput

0.458

High

1249220

LMBRL
Protein LMBR1L

1

0

High-throughput

0.458

High

1397436

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.458

High

1435299

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

944074

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

1

High-throughput

0.445

High

1133806

SL9A5
Sodium/hydrogen exchanger 5

1

1

High-throughput

0.445

High

1310952

ZNT8
Proton-coupled zinc antiporter SLC30A8

1

1

High-throughput

0.445

High

1436864

S27A6
Long-chain fatty acid transport protein 6

1

1

High-throughput

0.445

High

1436867

ZNT1
Proton-coupled zinc antiporter SLC30A1

1

1

High-throughput

0.445

High

1433440

Q9H4D1
Receptor-interacting serine/threonine-protein kinase 4

1

1

High-throughput

0.437

High

183968

S22A2
Solute carrier family 22 member 2

1

0

High-throughput

0.426

High

440732

FYN
Tyrosine-protein kinase Fyn

1

0

High-throughput

0.426

High

75538

B3KSH4
Huntingtin interacting protein 2, isoform CRA_a

1

18

High-throughput

0.417

High

1436861

CTNA3
Catenin alpha-3

2

0

High-throughput

0.316

High

277475

AVIL
Advillin

1

0

High-throughput

0.279

Low

1006304

CTG1B
Cancer/testis antigen 1

1

0

High-throughput

0.279

Low

1180410

KLH40
Kelch-like protein 40

1

0

High-throughput

0.279

Low

1204506

VWA2
von Willebrand factor A domain-containing protein 2

1

0

High-throughput

0.279

Low

1323927

KLH34
Kelch-like protein 34

1

0

High-throughput

0.279

Low

1340884

HUS1B
Checkpoint protein HUS1B

1

0

High-throughput

0.279

Low

1364770

PHYIP
Phytanoyl-CoA hydroxylase-interacting protein

1

0

High-throughput

0.279

Low

1396452

F167A
Protein FAM167A

1

0

High-throughput

0.279

Low

294340

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

1399029

YI001
Uncharacterized protein FLJ30774

1

0

High-throughput

0.249

Low

1185871

NSN5B
Putative NOL1/NOP2/Sun domain family member 5B

1

0

High-throughput

0.232

Low

1332138

CI163
Uncharacterized protein C9orf163

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025