Protein: KAPB
cAMP-dependent protein kinase type 2 (PKA 2) (EC 2.7.11.11)

Gene: KAPB, TPK2
Organism: Saccharomyces cerevisiae S288C
Interactions: 106
UniProt ID: P06245

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000932 - P-body
GO:0001403 - invasive growth in response to glucose limitation
GO:0004672 - protein kinase activity
GO:0004679 - AMP-activated protein kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

412929

KAPR
cAMP-dependent protein kinase regulatory subunit

18

20

Small-scale

0.988

High

409582

KAPC
cAMP-dependent protein kinase type 3

8

16

Small-scale

0.968

High

412611

KAPA
cAMP-dependent protein kinase type 1

8

14

Small-scale

0.966

High

412966

RPB7
DNA-directed RNA polymerase II subunit RPB7

3

1

Small-scale

0.847

High

412935

YAK1
Dual specificity protein kinase YAK1

2

16

High-throughput

0.799

High

412927

KAPB
cAMP-dependent protein kinase type 2

2

16

High-throughput

0.757

High

413010

PKH1
Serine/threonine-protein kinase PKH1

1

17

Small-scale

0.724

High

412942

RPB4
DNA-directed RNA polymerase II subunit RPB4

1

1

High-throughput

0.691

High

412948

KC11
Casein kinase I homolog 1

1

16

High-throughput

0.691

High

412965

MSN4
Zinc finger protein MSN4

1

4

High-throughput

0.691

High

412977

KSP1
Serine/threonine-protein kinase KSP1

1

17

High-throughput

0.691

High

412967

HSL1
Probable serine/threonine-protein kinase HSL1

1

9

High-throughput

0.665

High

412973

CHK1
Serine/threonine-protein kinase CHK1

1

7

High-throughput

0.665

High

412937

PHO85
Cyclin-dependent protein kinase PHO85

1

8

High-throughput

0.647

High

412947

KCC2
Calcium/calmodulin-dependent protein kinase II

1

8

High-throughput

0.647

High

412951

MEK1
Meiosis-specific serine/threonine-protein kinase MEK1

1

13

High-throughput

0.647

High

412954

KCC1
Calcium/calmodulin-dependent protein kinase I

1

7

High-throughput

0.647

High

412968

WHI3
Protein WHI3

1

2

Small-scale

0.647

High

412972

AKL1
Serine/threonine-protein kinase AKL1

1

15

High-throughput

0.647

High

412992

AZF1
Transcription factor AZF1

1

2

High-throughput

0.647

High

376578

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

9

Small-scale

0.618

High

412936

RPB3
DNA-directed RNA polymerase II subunit RPB3

2

2

High-throughput

0.611

High

412941

SFL1
Flocculation suppression protein

2

3

Small-scale

0.609

High

413001

MGA1
Protein MGA1

2

2

Small-scale

0.594

High

412940

HSP60
Heat shock protein 60, mitochondrial

2

17

High-throughput

0.584

High

412979

RIM4
Meiotic activator RIM4

1

10

High-throughput

0.579

High

412958

TREA
Cytosolic neutral trehalase

2

2

Small-scale

0.565

High

412999

JHD2
Histone demethylase JHD2

1

3

Small-scale

0.561

High

412988

SIP5
Protein SIP5

2

1

High-throughput

0.550

High

339957

KPYK1
Pyruvate kinase 1

1

4

Small-scale

0.536

High

413000

KPYK2
Pyruvate kinase 2

1

4

Small-scale

0.536

High

375201

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

2

High-throughput

0.536

High

389667

CDC25
Cell division control protein 25

1

4

High-throughput

0.536

High

412928

SYTM
Threonine--tRNA ligase, mitochondrial

1

1

High-throughput

0.536

High

412930

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

4

High-throughput

0.536

High

412945

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

1

1

High-throughput

0.536

High

412946

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

1

1

High-throughput

0.536

High

412950

SPT6
Transcription elongation factor SPT6

1

1

High-throughput

0.536

High

412955

SPT5
Transcription elongation factor SPT5

1

2

High-throughput

0.536

High

412956

RPB9
DNA-directed RNA polymerase II subunit RPB9

1

1

High-throughput

0.536

High

412962

PMD1
Negative regulator of sporulation PMD1

1

1

High-throughput

0.536

High

412969

TAF14
Transcription initiation factor TFIID subunit 14

1

1

High-throughput

0.536

High

412980

RPB11
DNA-directed RNA polymerase II subunit RPB11

1

1

High-throughput

0.536

High

412993

T2FA
Transcription initiation factor IIF subunit alpha

1

1

High-throughput

0.536

High

413002

MDS3
Negative regulator of sporulation MDS3

1

1

High-throughput

0.536

High

413013

IWS1
Transcription factor SPN1

1

2

High-throughput

0.536

High

413019

YP247
WD repeat-containing protein YPL247C

1

7

High-throughput

0.536

High

412982

GPB2
Guanine nucleotide-binding protein subunit beta 2

1

2

Small-scale

0.527

High

412943

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

1

0

High-throughput

0.513

High

412944

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

0

High-throughput

0.513

High

412986

RTR1
RNA polymerase II subunit B1 CTD phosphatase RTR1

1

0

High-throughput

0.513

High

412989

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

1

0

High-throughput

0.513

High

412994

T2FB
Transcription initiation factor IIF subunit beta

1

0

High-throughput

0.513

High

412998

GPN1
GPN-loop GTPase 1

1

0

High-throughput

0.513

High

412939

IRA2
Inhibitory regulator protein IRA2

1

8

Small-scale

0.501

High

412952

PAT1
Deadenylation-dependent mRNA-decapping factor PAT1

1

3

Small-scale

0.501

High

412959

SMY1
Kinesin-related protein SMY1

1

5

High-throughput

0.501

High

412961

PAH1
Phosphatidic acid phosphohydrolase 1

1

2

Small-scale

0.501

High

412963

RGT1
Glucose transport transcription regulator RGT1

1

2

Small-scale

0.501

High

412971

PUR92
Bifunctional purine biosynthesis protein ADE17 [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase

1

1

High-throughput

0.501

High

412976

IF5
Eukaryotic translation initiation factor 5

1

4

Small-scale

0.501

High

412981

DHH1
ATP-dependent RNA helicase DHH1

1

14

Small-scale

0.501

High

412990

6P21
6-phosphofructo-2-kinase 1

1

7

High-throughput

0.501

High

412996

IDS2
IME2-dependent-signaling protein

1

1

High-throughput

0.501

High

413003

PDK2
[Pyruvate dehydrogenase

1

7

High-throughput

0.501

High

413016

STB3
Protein STB3

1

1

High-throughput

0.501

High

342612

ENO1
Enolase 1

1

3

High-throughput

0.500

High

378254

LEU3
3-isopropylmalate dehydrogenase

1

2

High-throughput

0.500

High

410847

PDC1
Pyruvate decarboxylase isozyme 1

1

1

High-throughput

0.500

High

412978

YHI0
Putative proline--tRNA ligase YHR020W

1

2

High-throughput

0.500

High

412983

SAHH
Adenosylhomocysteinase

1

2

High-throughput

0.500

High

412985

IMB4
Importin subunit beta-4

1

4

High-throughput

0.500

High

412984

GIP2
GLC7-interacting protein 2

1

2

High-throughput

0.489

High

409927

NOT3
General negative regulator of transcription subunit 3

1

1

Small-scale

0.481

High

413018

NOT5
General negative regulator of transcription subunit 5

1

1

Small-scale

0.481

High

412932

PCKA
Phosphoenolpyruvate carboxykinase

1

0

High-throughput

0.480

High

413011

KYNU
Kynureninase

1

0

High-throughput

0.480

High

413014

PEX19
Peroxisomal membrane protein import receptor PEX19

1

0

High-throughput

0.480

High

413015

CLP1
mRNA cleavage and polyadenylation factor CLP1

1

0

High-throughput

0.480

High

410724

ILV5
Ketol-acid reductoisomerase, mitochondrial

1

0

High-throughput

0.479

High

412934

ALF
Fructose-bisphosphate aldolase

1

0

High-throughput

0.479

High

406644

RS3
Small ribosomal subunit protein uS3

1

2

Small-scale

0.479

High

412953

CDC20
APC/C activator protein CDC20

1

6

Small-scale

0.479

High

412964

SMY2
Protein SMY2

1

1

High-throughput

0.479

High

413012

NEJ1
Non-homologous end-joining protein 1

1

1

Small-scale

0.479

High

412938

GAP1
General amino-acid permease GAP1

1

3

Small-scale

0.457

High

412949

MBR1
Mitochondrial biogenesis regulation protein 1

1

2

High-throughput

0.457

High

412957

DGR2
2-deoxy-glucose resistant protein 2

1

5

High-throughput

0.457

High

412960

ISF1
Increasing suppression factor 1

1

2

High-throughput

0.457

High

412970

MNR2
Manganese resistance protein MNR2

1

4

High-throughput

0.457

High

412995

IGD1
Inhibitor of glycogen debranching 1

1

2

High-throughput

0.457

High

412997

AVT1
Vacuolar amino acid transporter 1

1

4

High-throughput

0.457

High

413005

YIF1
Protein transport protein YIF1

1

3

High-throughput

0.457

High

413007

YP077
Uncharacterized protein YPL077C

1

1

High-throughput

0.457

High

413008

NGL3
Probable RNA exonuclease NGL3

1

1

High-throughput

0.457

High

413009

ADD37
Alpha1-proteinase inhibitor-degradation deficient protein 37

1

2

High-throughput

0.457

High

412931

HSP72
Heat shock protein SSA2

1

9

High-throughput

0.445

High

412933

SSB1
Ribosome-associated molecular chaperone SSB1

1

9

High-throughput

0.445

High

412987

SSB2
Ribosome-associated molecular chaperone SSB2

1

9

High-throughput

0.445

High

413006

UBC7
Ubiquitin-conjugating enzyme E2 7

1

0

High-throughput

0.438

High

412975

YB75
Uncharacterized protein YBR225W

1

0

High-throughput

0.279

Low

412974

FTH1
Iron transporter FTH1

1

0

High-throughput

0.261

Low

412991

SNL1
HSP70 co-chaperone SNL1

1

0

High-throughput

0.261

Low

413004

DAM1
DASH complex subunit DAM1

1

0

Small-scale

0.261

Low

413017

PEX11
Peroxisomal membrane protein PMP27

1

0

High-throughput

0.261

Low


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Last updated: 15 Jul 2024